Results 211 to 220 of about 1,839,456 (290)

Genetic Engineering Methods in Primary T Cells

Advanced Therapeutics, EarlyView.
Primary T cells can be engineered to confer them with novel therapeutic functions, allowing them to treat a variety of conditions. Genetic engineering can be either stable or transient, aiming to either express or inhibit a target gene. This review discusses the various genetic engineering tools available as well as their characteristics and ...
Anthony Youssef, Hui‐Shan Li
wiley   +1 more source

AN EARLY SPECIMEN OF TOTAL ENUCLEATION OF THE PROSTATE REMOVED BY THE LATE Mr. McGILL [PDF]

, 1907
James Forsyth
openalex   +1 more source

Prostate cancer in men under 50: the impact of race/ethnicity and family history. [PDF]

Ann Med
Chen L, Zhang Y, Meng QH.
europepmc   +1 more source

Understanding miR‐200c: an Important Player in Resistance to Cancer Treatment

Advanced Therapeutics, EarlyView.
How can one microRNA alter cancer's response to therapy? miR‐200c plays a central role in therapeutic resistance by modulating epithelial‐mesenchymal transition, apoptosis, cancer stemness features, and drug efflux. This review outlines the context‐dependent functions of miR‐200c in various cancers and highlights its potential as both a biomarker and a
Fatma Sanli, Omer Faruk Karatas
wiley   +1 more source

Transurethral Resection of the Prostate [PDF]

, 1937
K. M. Walker
openalex   +1 more source

An intervention mapping approach to the development and evaluation of a community-based prostate cancer early detection programme in Nigeria. [PDF]

PLOS Glob Public Health
Tolani MA, Agbo CA, Umar SS, Paciorek A, Ojewola RW, Mohammed F, Maiga M, Kaninjing E, Ahmed M, DeBoer R.   +9 more
europepmc   +1 more source

SMYD3 Promotes Immune Evasion in Clear Cell Renal Cell Carcinoma via SREBP1‐Mediated Transactivation of CD47

Advanced Science, EarlyView.
Cancer cell‐intrinsic SMYD3 orchestrates an immunosuppressive microenvironment and impairs the response to PD‐1 blockade by reprogramming immune cells landscape in the tumor microenvironment of clear cell renal cell carcinoma (ccRCC). The immunomodulatory function of SMYD3 is mediated via the SREBP1/CD47 pathway.
Zhengfang Liu, Xiumei Zhao, Maolin Zang, Huiyang Yuan, Xin Qin, Xiaofeng Li, Shuo Zhao, Ruirong Tan, Keqiang Yan, Li Liu, Yidong Fan, Ning Zhang, Benkang Shi, Bo Han, Shouzhen Chen   +14 more
wiley   +1 more source

ASCL1 regulates and cooperates with FOXA2 to drive terminal neuroendocrine phenotype in prostate cancer. [PDF]

JCI Insight
Nouruzi S, Namekawa T, Tabrizian N, Kobelev M, Sivak O, Scurll JM, Cui CJ, Ganguli D, Zoubeidi A.   +8 more
europepmc   +1 more source

Glucose Deprivation‐Induced Disulfidptosis via the SLC7A11‐INF2 Axis: Pan‐Cancer Prognostic Exploration and Therapeutic Validation

Advanced Science, EarlyView.
Glucose deprivation or GLUT1 inhibition induces disulfidptosis in SLC7A11high ovarian cancer cells by promoting cystine accumulation, NADPH/ATP depletion, and F‐actin disulfide formation. SLC7A11 interacts with INF2 to further increase H₂O₂ levels and impair mitochondrial fission, suppressing cell migration. Targeting the SLC7A11–INF2 axis represents a
Zhenyu Song, Qiuming Yao, Lina Huang, Dan Cui, Jun Xie, Leilei Wu, Jianfeng Huang, Bo Zhai, Dan Liu, Xiao Xu   +9 more
wiley   +1 more source

An account of a small lobe of the human prostate gland, which has not before been taken notice of by anatomists [PDF]

Everard Home
openalex   +1 more source