Results 251 to 260 of about 1,302,201 (345)

Trial Design and Objectives for Castration-Resistant Prostate Cancer: Updated Recommendations From the Prostate Cancer Clinical Trials Working Group 3.

Journal of Clinical Oncology, 2016
H. Scher, M. Morris, W. Stadler, C. Higano, E. Basch, K. Fizazi, E. Antonarakis, T. Beer, M. Carducci, K. Chi, P. Corn, J. D. de Bono, R. Dreicer, D. George, E. Heath, M. Hussain, W. Kelly, Glenn Liu, C. Logothetis, D. Nanus, M. Stein, D. Rathkopf, S. Slovin, C. Ryan, O. Sartor, E. Small, Matthew R. Smith, C. Sternberg, M. Taplin, G. Wilding, P. Nelson, L. Schwartz, S. Halabi, P. Kantoff, A. Armstrong   +34 more
semanticscholar   +1 more source

Laser and the prostate [PDF]

Central European Journal of Urology, 2016
openaire   +3 more sources

Nrf2 Drives Epigenetic Reprogramming and Acts as the Master Regulator of KLF4 Expression and Activity in Arsenic‐Induced Transformation

Advanced Science, EarlyView.
Nrf2 isn't just a protector—it's a driver of cancer stemness. The study uncovers how arsenic‐activated Nrf2 directly upregulates KLF4, a key pluripotency factor, fueling oncogenic reprogramming. Through enhancer activation and self‐reinforcing loop, Nrf2 and KLF4 co‐opt gene networks linked to epithelial‐to‐mesenchymal transition and tumor growth ...
Ziwei Wang, Zhuoyue Bi, Jessica Bamrah, Yiran Qiu, Wenxuan Zhang, Bandar Saeed Almutairy, Haoyan Ji, John D. Haley, Chitra Thakur, Fei Chen   +9 more
wiley   +1 more source

Associations between XRCC1-Arg399Gln polymorphism and the risk of prostate cancer: an updated meta-analysis. [PDF]

Amino Acids
Deng J, Xu L, Zhou J, Huang H.
europepmc   +1 more source

5’‐Methylthioadenosine Metabolic Reprogramming Drives H3K79 Monomethylation‐Mediated PAK2 Upregulation to Promote Cadmium‐Induced Breast Cancer Progression by Impairing Autophagic Flux

Advanced Science, EarlyView.
Cadmium, a carcinogenic heavy metal, drives breast cancer progression via metabolic reprogramming and autophagic flux disruption. Multi‐omics revealed cadmium‐induced 5'‐methylthioadenosine depletion activates DOT1L‐mediated H3K79me1 at PAK2 promoter, upregulating PAK2 to block autophagy and driving malignancy. Clinically, 5'‐methylthioadenosine levels
Jingdian Li, Ping Deng, Tengfei Fan, Yuchen Qu, Miduo Tan, Yidan Liang, Peng Gao, Yongchun Peng, Mingke Qin, Sheng Jie, Rongrong Hao, Liting Wang, Lei Zhang, Chunhai Chen, Mindi He, Qinlong Ma, Yan Luo, Li Tian, Jia Xie, Mengyan Chen, Rui Tian, Min Li, Zhengping Yu, Zhou Zhou, Huifeng Pi   +24 more
wiley   +1 more source

Department of Error. [PDF]

Lancet
europepmc   +1 more source

Advanced Microfluidics for Single Cell‐Based Cancer Research

Advanced Science, EarlyView.
Cutting‐edge microfluidic platforms are transforming single‐cell cancer research. This review highlights advanced technologies, from droplet microfluidics to tumour‐chips, that enable functional and spatial single‐cell analyses. By integrating biosensing, immune components, and patient‐derived materials, these systems offer new insights into tumour ...
Adriana Carneiro, Marta Aranda Palomer, Margarida Esteves, Carolina Rodrigues, José Maria Fernandes, Francisca Oliveira, Alexandra Teixeira, Carlos Honrado, Lorena Dieguez, Sara Abalde‐Cela, Miguel Xavier   +10 more
wiley   +1 more source

Does the digital rectal exam still provide value in the age of MRI? [PDF]

Can Urol Assoc J
Albers P, Miandashti N, Broomfield S, Kinnaird A.   +3 more
europepmc   +1 more source

A CASE OF ENORMOUS PROSTATIC CALCULUS.1

, 1904
FRANK G. LYDSTON
openalex   +2 more sources

SOX2 promotes lineage plasticity and antiandrogen resistance in TP53- and RB1-deficient prostate cancer

Science, 2017
P. Mu, Zeda Zhang, M. Benelli, W. Karthaus, Elizabeth A. Hoover, Chi-Chao Chen, John Wongvipat, Sheng-Yu Ku, D. Gao, Z. Cao, Neel Shah, E. Adams, W. Abida, Philip A Watson, D. Prandi, Chun-Hao Huang, E. de Stanchina, S. Lowe, L. Ellis, H. Beltran, M. Rubin, D. Goodrich, F. Demichelis, C. Sawyers   +23 more
semanticscholar   +1 more source