Results 131 to 140 of about 5,889,184 (390)

Serum Glutamate Levels Correlate with Gleason Score and Glutamate Blockade Decreases Proliferation, Migration, and Invasion and Induces Apoptosis in Prostate Cancer Cells [PDF]

, 2012
Shahriar Koochekpour, Sunipa Majumdar, Gissou Azabdaftari, Kristopher Attwood, Ray Scioneaux, Dhatchayini Subramani, Charles Manhardt, Giovanni D. Lorusso, Stacey S. Willard, Hillary Thompson, Mojgan Shourideh, Katayoon Rezaei, Oliver Sartor, James L. Mohler, Robert L. Vessella   +14 more
openalex   +1 more source

Metronomic Chemotherapy in Prostate Cancer [PDF]

, 2022
Piotr J. Wysocki, Maciej Tadeusz Lubaś, Malgorzata L. Wysocka   +2 more
openalex   +1 more source

Darolutamide in Nonmetastatic, Castration‐Resistant Prostate Cancer

New England Journal of Medicine, 2019
BACKGROUND Darolutamide is a structurally unique androgen‐receptor antagonist that is under development for the treatment of prostate cancer. We evaluated the efficacy of darolutamide for delaying metastasis and death in men with nonmetastatic ...
K. Fizazi, N. Shore, T. Tammela, A. Ulys, E. Vjaters, S. Polyakov, M. Jievaltas, M. Luz, B. Alekseev, I. Kuss, C. Kappeler, A. Snapir, T. Sarapohja, Matthew R. Smith   +13 more
semanticscholar   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source

Screening for Prostate Cancer: US Preventive Services Task Force Recommendation Statement

Journal of the American Medical Association (JAMA), 2018
Importance In the United States, the lifetime risk of being diagnosed with prostate cancer is approximately 13%, and the lifetime risk of dying of prostate cancer is 2.5%. The median age of death from prostate cancer is 80 years.
D. Grossman, S. Curry, D. Owens, Kirsten Bibbins-Domingo, A. Caughey, K. Davidson, Chyke A Doubeni, M. Ebell, J. Epling, A. Kemper, A. Krist, Martha Y. Kubik, C. Landefeld, C. Mangione, Michael Silverstein, M. Simon, A. Siu, Chien-Wen Tseng   +17 more
semanticscholar   +1 more source

Actin dynamics controlled by IqgC, a RasGAP at the crossroads between the IQGAP and fungal GAP1 families

FEBS Open Bio, EarlyView.
IqgC is a RasGAP from Dictyostelium discoideum. IqgC binds RasG via its RasGAP domain and deactivates it on macroendocytic cups, thereby suppressing the uptake of fluid and particles. IqgC has a positive effect on cell‐substratum adhesion, and its RGCt domain is required for recruitment to ventral foci.
Vedrana Filić, Darija Putar, Lucija Mijanović, Igor Weber   +3 more
wiley   +1 more source

Genetic ancestry concordant RNA splicing in prostate cancer involves oncogenic genes and associates with recurrence

npj Precision Oncology
Black men suffer disproportionately from prostate cancer (PCa) compared to men of other races and ethnicities. Comparing the molecular landscape of PCa among Black and White patients has the potential to identify targets for development of new precision ...
Muthana Al Abo, Wen-Chi Foo, Lauren E. Howard, Shannon McGue, Bonnie Lacroix, Julie Kephart, Angela Clayton, Blair Thornburg, Monika Anand, Michael B. Rothberg, Shannon J. McCall, Jiaoti Huang, Thomas A. Esther, Judd W. Moul, Michael N. Ferrandino, Thomas J. Polascik, Cary N. Robertson, Brant A. Inman, Andrew J. Armstrong, Yuan Wu, Terry Hyslop, Daniel J. George, Steven R. Patierno, Jennifer A. Freedman   +23 more
doaj   +1 more source

Significance of BRCA2 and RB1 Co-loss in Aggressive Prostate Cancer Progression [PDF]

, 2019
Goutam Chakraborty, Joshua Armenia, Ying Z. Mazzu, Subhiksha Nandakumar, Konrad H. Stopsack, Mohammad Atiq, Kazumasa Komura, Lina Jehane, Rahim Hirani, Kalyani Chadalavada, Yuki Yoshikawa, Nabeela Khan, Yu Chen, Wassim Abida, Lorelei A. Mucci, Gwo‐Shu Mary Lee, Gouri J. Nanjangud, Philip W. Kantoff   +17 more
openalex   +1 more source

Interplay between RNA‐protein interactions and RNA structures in gene regulation

FEBS Open Bio, EarlyView.
Methodological advances in mapping transcriptome‐wide RNA‐protein interactions and RNA structures have started to uncover the potential of RNP conformations in gene regulation. Competing RNA–RNA, RNA‐protein and protein–protein interactions shape the compaction and function of RNPs throughout their lifetime and may provide novel therapeutic targets in ...
Jenni Rapakko, Mauro Scaravilli, Minna‐Liisa Änkö   +2 more
wiley   +1 more source

Combination therapy overcomes secondary PARPi resistance in ATM-deficient prostate cancer

npj Precision Oncology
PARP inhibitors (PARPi) are approved treatments for patients with metastatic prostate cancer (mPC); tumors with homologous recombination repair (HRR) defects are particularly sensitive to this drug class.
Sara Arce-Gallego, Victor Esquefa, Heura Domenech, Andrei Salca, Daniel Aguilar, Teresa Casals, Gisela Mir, Sara Simonetti, Anna Oliveira, Lara de Llobet, Antje Neeb, Julian Brandariz, Nicolas Anselmino, Irene Casanova-Salas, Nicolas Herranz, Violeta Serra, Johann S. de Bono, Joaquin Mateo   +17 more
doaj   +1 more source