Results 221 to 230 of about 1,150,712 (337)

Advances and Strategies in Enhancing mRNA Cancer Vaccines

open access: yesAdvanced Materials, EarlyView.
Messenger RNA (mRNA) vaccines offer a powerful approach for cancer immunotherapy, but their clinical impact remains limited by delivery challenges and suboptimal immune activation. This review discusses key biological barriers and design strategies—including structural optimization, immunomodulation, organ targeting delivery, and advanced nanocarriers ...
Miao Zhang   +4 more
wiley   +1 more source

Development of a Sensitive Electrochemical Aptasensor for Non‐Small Cell Lung Cancer Extracellular Vesicle Detection

open access: yesAdvanced Materials Interfaces, EarlyView.
A novel electrochemical aptasensor enables the selective detection of lung cancer‐derived EVs by targeting the CD44 surface marker. The sensor uses a self‐assembled monolayer (SAM) for aptamer immobilization and achieves label‐free EV detection through electrochemical impedance spectroscopy.
Zarinah M. Amin   +3 more
wiley   +1 more source

Association of marginalization and PSMA-PET in prostate cancer An analysis of the Ontario PSMA-PET Registry for Recurrent Prostate Cancer. [PDF]

open access: yesCan Urol Assoc J
Tan VS   +14 more
europepmc   +1 more source

Synthesis of Tertiary Amine Assisted Cytocompatible Zn‐MOFs for Efficient Nucleic Acid Encapsulation and Delivery to Prostate Cancer Cells

open access: yesAdvanced Materials Interfaces, EarlyView.
The study explores the influence of a tertiary amine in loading genetic material in a hybrid composite. The study highlights how structural attributes and chemical composition govern the crystallinity and cytocompatibility of ZIF‐biocomposites that effectively deliver nucleic acid to cancer cells.
Shakil Ahmed Polash   +3 more
wiley   +1 more source

Overdiagnosis and Overtreatment in Prostate Cancer. [PDF]

open access: yesDiseases
Dushimova Z   +7 more
europepmc   +1 more source

Heterogeneity Landscape of Circulating Tumor Cells in Clinical Utility

open access: yesAdvanced Therapeutics, EarlyView.
This study reports the heterogeneity spectrum of circulating tumor cells. The factors involved in the spectrum promote CTCs to overcome barriers in the metastatic cascade but impact the clinical outcome of cancer patients. In summary, the heterogeneities in association with CTCs ultimately reduce patient survival and facilitate increasing mortality of ...
Md Kowsar Alam   +5 more
wiley   +1 more source

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