Results 231 to 240 of about 1,172,272 (355)

Prostate Cancer [PDF]

, 1981
RCB Pugh
openalex   +1 more source

From Design to Outcome: The Role of Bi‐ and Multifunctional Ligands in Modern Therapeutics

Advanced Therapeutics, EarlyView.
This review highlights the innovative use of bi‐ and multifunctional ligands for precision therapeutics. From strategic linker design to bioorthogonal conjugation and nanoscaffold integration, these approaches enable precise targeting, high‐resolution receptor mapping, and enhanced drug delivery.
Célia Bouacha, Séverine Denoyelle, Sonia Cantel   +2 more
wiley   +1 more source

Prostatic Malakoplakia as a Mimic of Prostate Cancer Progression. [PDF]

Cureus
Spiker M, Pilley JD, Vaidya NK, Manesh R.   +3 more
europepmc   +1 more source

Luteinising hormone releasing hormone analogue for prostatic cancer [PDF]

, 1985
G. Williams
openalex   +1 more source

Enhancing the Effectiveness of Chemotherapy in Osteosarcoma by Targeting Tumour‐Associated Macrophages (TAMs) through STING Activation

Advanced Therapeutics, EarlyView.
Osteosarcoma isa highly aggressive bone cancer with an immunosuppressive tumor microenvironment that limits immunotherapy. This study explores STING pathway activation to reprogram tumor‐associated macrophages into a tumoricidal M1‐like phenotype and enhance doxorubicin efficacy. Results show that doxorubicin alone failed to activate the STING pathway,
Jordan C. O'Donoghue, Amanda Guitián‐Caamaño, Maeve Boyce, Fiona E. Freeman   +3 more
wiley   +1 more source

Decoding Microbiome's Role in Prostate Cancer Progression and Treatment Response. [PDF]

Diseases
Sakellakis M, Resta P, Papagianni E, Procter KA, Belouka I, Gioti K, Anthouli-Anagnostopoulou F, Chaniotis D, Beloukas A.   +8 more
europepmc   +1 more source

Glucose Deprivation‐Induced Disulfidptosis via the SLC7A11‐INF2 Axis: Pan‐Cancer Prognostic Exploration and Therapeutic Validation

Advanced Science, EarlyView.
Glucose deprivation or GLUT1 inhibition induces disulfidptosis in SLC7A11high ovarian cancer cells by promoting cystine accumulation, NADPH/ATP depletion, and F‐actin disulfide formation. SLC7A11 interacts with INF2 to further increase H₂O₂ levels and impair mitochondrial fission, suppressing cell migration. Targeting the SLC7A11–INF2 axis represents a
Zhenyu Song, Qiuming Yao, Lina Huang, Dan Cui, Jun Xie, Leilei Wu, Jianfeng Huang, Bo Zhai, Dan Liu, Xiao Xu   +9 more
wiley   +1 more source

Targeting GSTM3 for therapeutic potential in advanced prostate cancer. [PDF]

BMC Cancer
Seven D, Dalan AB, Bayrak ÖF.
europepmc   +1 more source

Epigenetic Activation of CCDC183‐AS1 Promotes Osteoclastogenesis and Prostate Cancer Bone Metastasis Through the FUBP1/LIGHT Axis

Advanced Science, EarlyView.
CCDC183‐AS1 overexpression enhanced the ability of PCa cells to spread to the bone by inducing osteoclastogenesis. Mechanistically, CCDC183‐AS1 interacted with FUBP1 and enhanced its stability, which promoted the transcription of TNFSF14 (LIGHT). Copy number gain‐induced KDM5C epigenetically upregulated CCDC183‐AS1 expression by recruiting TET1 to the ...
Chuandong Lang, Xiangyu Mu, Kun Chen, Xinwen Wang, Yuluo Rong, Jia Wang, Zongcheng Yang, Chi Yin, Yuhu Dai, Jun Xiao, Wenzhi Zhang   +10 more
wiley   +1 more source

Evaluating the prognosis of prostate cancer through metabolic pathways. [PDF]

Discov Oncol
Su Q, Hu Y, Dai B.
europepmc   +1 more source