Results 241 to 250 of about 5,889,184 (390)

Integrative Clinical Genomics of Advanced Prostate Cancer

Cell, 2015
D. Robinson, E. Allen, Yi-Mi Wu, N. Schultz, R. Lonigro, J. Mosquera, B. Montgomery, M. Taplin, C. Pritchard, G. Attard, H. Beltran, W. Abida, R. Bradley, J. Vinson, Xuhong Cao, Pankaj Vats, L. Kunju, M. Hussain, F. Feng, S. Tomlins, K. Cooney, David C. Smith, Christine A Brennan, J. Siddiqui, R. Mehra, Yu Chen, D. Rathkopf, M. Morris, S. Solomon, J. Durack, V. Reuter, A. Gopalan, Jianjiong Gao, M. Loda, R. Lis, M. Bowden, S. Balk, Glenn C. Gaviola, C. Sougnez, Manaswi Gupta, E. Yu, E. Mostaghel, Heather H. Cheng, Hyojeong Mulcahy, L. True, S. Plymate, H. Dvinge, R. Ferraldeschi, P. Flohr, S. Miranda, Z. Zafeiriou, N. Tunariu, J. Mateo, R. Pérez-López, F. Demichelis, B. Robinson, M. Schiffman, D. Nanus, S. Tagawa, Alexandros Sigaras, Kenneth Eng, O. Elemento, A. Sboner, E. Heath, H. Scher, K. Pienta, P. Kantoff, J. Bono, M. Rubin, P. Nelson, L. Garraway, C. Sawyers, A. Chinnaiyan   +72 more
semanticscholar   +1 more source

A Patient‐Derived Organoid Biobank of Adamantinomatous Craniopharyngioma as a Platform for Drug Discovery

Advanced Science, EarlyView.
This study successfully establishes adamantinomatous craniopharyngioma (ACP) patient‐derived organoids (PDOs) that preserve the histopathological and genetic features of the original tumors. Through drug sensitivity assays and subsequent mechanistic analyses, the study demonstrates that Ceritinib exerts its inhibitory effects on ACP PDO growth by ...
Huarong Zhang, Chaohu Wang, Jun Fan, Zexin Chen, Haoying Yu, Yawen Bai, Tingcheng Zhang, Qianchao Zhu, Yiwen Feng, Peirong Niu, Jiaqian Chen, Liping Yang, Xueying Li, Lei Yu, Songtao Qi, Yi Liu   +15 more
wiley   +1 more source

Neoadjuvant Therapies for Prostate Cancer-Current Paradigms and Future Directions. [PDF]

Cancers (Basel)
Sandhu K, Al-Khanaty A, Hennes D, Chen D, Dinneen E, Delgado C, Lawrentschuk N, Eapen RS, Murphy DG, Perera M.   +9 more
europepmc   +1 more source

An examination of clinical differences between carriers and non-carriers of chromosome 8q24 risk alleles in a New Zealand Caucasian population with prostate cancer [PDF]

, 2016
Karen Bishop, Dug Yeo Han, Nishi Karunasinghe, Megan Goudie, Jonathan Masters, Lynnette R. Ferguson   +5 more
openalex   +1 more source

AR-V7 and resistance to enzalutamide and abiraterone in prostate cancer.

New England Journal of Medicine, 2014
E. Antonarakis, Changxue Lu, Hao Wang, Brandon S. Luber, M. Nakazawa, J. Roeser, Yan Chen, Tabrez A Mohammad, Yidong Chen, Helen L. Fedor, T. Lotan, Qizhi Zheng, A. D. De Marzo, J. Isaacs, W. Isaacs, R. Nadal, C. Paller, S. Denmeade, M. Carducci, M. Eisenberger, Jun Luo   +20 more
semanticscholar   +1 more source

Tumor‐Derived CDC37 Inhibits Antigen Cross‐Presentation in Dendritic Cells and Impairs Anti‐Tumor Immunity in Breast Cancer

Advanced Science, EarlyView.
Extracellular vesicle (EV)‐packaged CDC37 are released from TMBhiCTLlo breast cancer cells with high CDC37 expression, and internalized into endo/phagosomes of dendritic cells (DCs). Within these compartments, CDC37 locked HSP90–antigen complex, preventing antigen release into the cytosol.
Ruxin Wang, Yunyi Zhang, Xiangyu Meng, Jianli Zhao, Yue Xing, Qian Ouyang, Ning Zhang, Huiping Chen, Nanyan Miao, Erwei Song, Di Huang   +10 more
wiley   +1 more source

The Role of Nuclear Medicine in Prostate Cancer. [PDF]

Diagnostics (Basel)
Grozdic Milojevic I, Milojevic B, Skrijelj D, Bumbasirevic U, Janicic A, Kajmakovic B, Sobic-Saranovic D, Artiko V, Beatovic S.   +8 more
europepmc   +1 more source

A Unique Chimeric RNA: ERCC1‐iASPP Drives Benzo[a]pyrene‐Induced Lung Carcinogenesis via Dual Coding and Non‐Coding Mechanisms

Advanced Science, EarlyView.
The chimeric RNA ERCC1‐iASPP possesses dual coding and non‐coding functions, synergistically accelerating the process of cellular malignant transformation. Abstract Genetic variation at 19q13.3 critically modulates chemical carcinogen‐induced lung carcinogenesis, particularly in mediating the activity of benzo[a]pyrene (B[a]P), a major polycyclic ...
Mingming Shan, Mingyang Xiao, Liang Zhang, Shen Wang, Jiahang Wu, Kang Cao, Yujin Li, Guopei Zhang, Junwei Xie, Xiaobo Lu   +9 more
wiley   +1 more source

Metabolomic Insights into Prostate Cancer Treatment and Relapse. [PDF]

Cancers (Basel)
Lundquist K, Antti H, Thellenberg Karlsson C.   +2 more
europepmc   +1 more source

Genomic and phenotypic heterogeneity in prostate cancer

Nature reviews. Urology, 2020
Michael C. Haffner, W. Zwart, M. Roudier, L. True, W. Nelson, J. Epstein, A. D. De Marzo, P. Nelson, S. Yegnasubramanian   +8 more
semanticscholar   +1 more source