Results 251 to 260 of about 5,889,184 (390)

Amphiregulin and Epiregulin Confer Radioresistance in Esophageal Squamous Cell Carcinoma Through Oxidative Phosphorylation

Advanced Science, EarlyView.
Oxidative phosphorylation (OXPHOS) activity serves as a critical metabolic determinant of radiotherapy outcomes in esophageal squamous cell carcinoma (ESCC). The CEBPB/AREG/EREG axis drives radioresistance in ESCC by reprogramming OXPHOS. AREG and EREG function as predictive biomarkers for nCRT response and prognosis of ESCC patients.
Zhang Lin, Meilian Yao, Xin Xu, Dong Zhang, Lei Xu, Ling Rong, Xiaohang Wang, Yi Duan, Chengkun Chen, Jun Gu, Yao Zhang, Qiang Liu, Qing Ye, Gaoping Cui, Yujun Hao, Xiumei Ma   +15 more
wiley   +1 more source

Prostate cancer characteristics in fathers and risk of early onset high-risk prostate cancer in sons. [PDF]

Int J Cancer
Lin E, Garmo H, Beckmann K, Bratt O, Akre O, Stattin P, Gedeborg R.   +6 more
europepmc   +1 more source

CYP4X1/sEH‐Dependent Endocannabinoid Metabolism Drives Fibroblast‐Mediated Immunosuppression to Limit Immunotherapy in Colon Cancer

Advanced Science, EarlyView.
A proposed mechanism to explain the role of CYP4X1/sEH‐14,15‐EET‐EA system in colon cancer immune escape. 14,15‐EET‐EA, 14,15‐epoxyeicosatrienoic acid‐ethanolamide; sEH, soluble epoxide hydrolase; CYP4X1, cytochrome P450 4X1; GPR119, G‐protein coupled receptor 119; EGFR, epidermal growth factor receptor; Gs, Gαs subunit; cAMP, cyclic adenosine ...
Min Mo, Xuewei Chen, Yanzhuo Liu, Chenlong Wang, Xuehan Chen, Nan Zhang, Nan He, Ying Li, Jingyi Wang, Honglei Chen, Jing Yang   +10 more
wiley   +1 more source

Competition for nutrients or cell intrinsic programming? – Metabolic mechanisms behind the tumor promoting immune microenvironment in cancer

Signal Transduction and Targeted Therapy, 2021
Yuequn Niu, Thomas Mayr, Michael H. Muders   +2 more
doaj   +1 more source

Significance of EVs in Prostate Cancer Bone Metastases. [PDF]

Int J Mol Sci
Ito K, Tamura T, Urabe F, Sakamoto S, Kimura T, Egawa S, Ochiya T.   +6 more
europepmc   +1 more source

Interstitial Granulomatous Dermatitis in a Patient with Prostate Cancer

, 2017
So Min Kim, Sang Hyun Cho, Jeong Deuk Lee, Hei Sung Kim   +3 more
openalex   +1 more source

Metformin Impairs Breast Cancer Growth through the Inhibition of PRMT6

Advanced Science, EarlyView.
Metformin has a biological activity against breast cancer. However, it is largely unknown about its precise therapeutic targets. Here, histone arginine methyltransferase PRMT6 is identified as a new anti‐cancer target for metformin. Metformin directly binds PRMT6 and inhibits its ability to catalyze histone H3R2 asymmetric dimethylation (H3R2me2a ...
Yinsheng Wu, Xinlin Xu, Yue Tong, Min Wang, Feng Ge, Min Wu, Yunlong Wang, Gang Chen, Xilan Yu, Shanshan Li   +9 more
wiley   +1 more source

Network and Gene Set Enrichment Analysis of Adipokine Drivers of Prostate Cancer; Unravelling the Mechanistic Link Between Excess Adiposity and Prostate Cancer Risk. [PDF]

Cancer Med
Dovey Z, Bort ET, Mechanick JI.
europepmc   +1 more source

Real-World Treatment Patterns in Patients with Castrate-Resistant Prostate Cancer and Bone Metastases.

, 2019
Lonnie Wen, Adriana Valderrama, Mary E. Costantino, Stacey Simmons   +3 more
openalex   +1 more source

PTBP1 Regulates DNMT3B Alternative Splicing by Interacting With RALY to Enhance the Radioresistance of Prostate Cancer

Haixia He, Qianghua Zhou, Yanjie Zhang, Yi Li, Lin Ding, Ting Shen, Sen Liu, Shengmeng Peng, Ming Huang, Hua Zhou, Liang Cheng, Ruihui Xie, Qiang Zhang, Junlin Lu, Liting Li, Jing Yang, Shoumin Bai, Tianxin Lin, Xu Chen   +18 more
openalex   +1 more source