Results 261 to 270 of about 1,172,272 (355)

Radionuclides Landscape in Prostate Cancer Theranostics. [PDF]

open access: yesInt J Mol Sci
Neagu M   +6 more
europepmc   +1 more source

Glycolytic Enzyme HK2 Phosphorylates nSMase1 to Promote Astrocytic Exosomes Biogenesis Contributing to Acute Ischemic Stroke Injury

open access: yesAdvanced Science, EarlyView.
This study reveals that the glycolytic enzyme HK2 mediates hypoxia‐induced astrocytic exosome biogenesis by directly phosphorylating nSMase1. These astrocytic exosomes impair brain endothelial tight junctions. Astrocyte‐specific knockdown of HK2 reduces exosome release and alleviates brain injury after MCAO.
Chen Chen   +12 more
wiley   +1 more source

Overview of Performance Indicators of Prostate Cancer Screening Trials. [PDF]

open access: yesEur Urol Open Sci
van Harten MJ   +3 more
europepmc   +1 more source

Lithium Exposure Causes Trophoblast Cuproptosis by Upregulating FOXO1/STEAP4 Axis in Unexplained Miscarriage

open access: yesAdvanced Science, EarlyView.
Li exposure up‐regulates FOXO1 expression levels and thus promotes FOXO1‐mediated STEAP4 transcription, up‐regulating STEAP4 levels. Subsequently, STEAP4 up‐regulates intracellular Cu+ ion levels and causes cuproptosis, which further induces miscarriage.
Shuaishuai Xing   +14 more
wiley   +1 more source

Abnormal β‐Hydroxybutyrylation Modification of ARG1 Drives Reprogramming of Arginine Metabolism to Promote the Progression of Colorectal Cancer

open access: yesAdvanced Science, EarlyView.
Alterations in arginine metabolism and β‐hydroxybutyrylation (Kbhb) modifications play a critical role in tumor progression. This study reveals valuable insights into arginine metabolism reprogramming involving the ARG1‐Kbhb/P300/SLC3A2 signaling axis and uncovers an effective therapy combining BHB with ARG1 inhibitor through conventional enzymatic and
Chuman Lin   +6 more
wiley   +1 more source

Comparison of Disease Progression From Prostate Cancer Diagnosis to Metastatic or Nonmetastatic Castrate-Resistant Prostate Cancer (CRPC) Patients: CaPA Study. [PDF]

open access: yesCancer Med
Costa P   +19 more
europepmc   +1 more source

PROGNOSTIC EVALUATION OF PROSTATIC CANCER BY GLEASON'S HISTOPATHOLOGIC GRADING AND TISSUE DHT LEVEL

open access: bronze, 1988
Yoshiteru Kohama   +6 more
openalex   +2 more sources

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