Results 141 to 150 of about 1,084,057 (356)

Cancer Stem Cells Shift Metabolite Acetyl‐Coenzyme A to Abrogate the Differentiation of CD103+ T Cells

Advanced Science, EarlyView.
Lei et al. demonstrate that cancer stem cells (CSCs) play a pivotal role in impairing the differentiation of CD103+ T cells in patients with non‐small‐cell lung cancer. The key mechanism involves CSC‐derived acetyl‐CoA, which disrupts CD103+ T cell differentiation by sequentially inducing acetylation and ubiquitination of the Blimp‐1 protein. Targeting
Jiaxin Lei, Huiyan Ji, Jing Guo, Mengdi Liu, Danhua Su, Yiran Zheng, Lin Xu, Qinghua Cao, Tao Ren, Jun Gui, Zhenke Wen   +10 more
wiley   +1 more source

CXCL12γ induces human prostate and mammary gland development

, 2020
Younghun Jung, Jin Koo Kim, Eunsohl Lee, Frank C. Cackowski, Ann M. Decker, Paul H. Krebsbach, Russell S. Taichman   +6 more
openalex   +2 more sources

Multicentric comparative analysis of Retzius versus Retzius sparing robotic assisted simple prostatectomy in the management of large prostate glands

, 2022
C. Surcel, Salam Najjar, Apostolos P. Labanaris, Vahudin Zugor, David Kajaia, Isabel Heidegger, I. Sinescu, Giorgio Gandaglia, Alexander Kretschmer, C. Surcel   +9 more
openalex   +1 more source

5′tRF‐GlyGCC Promotes Breast Cancer Progression via LDHA‐Mediated Glycolysis and Macrophage Polarization

Advanced Science, EarlyView.
5’tRF‐GlyGCC promotes breast cancer malignancy by binding to LDHA. This interaction, facilitated by FGFR1 and LDHA phosphorylation, enhances glycolysis. Additionally, 5’tRF‐GlyGCC/LDHA signaling recruits and polarizes macrophages into a pro‐tumor M2 state via CCL7, thus remodeling the tumor microenvironment.
Cheng Yi, Yunqing Lu, Xing Chang, Ying Wang, Jiawang Zhou, Guoyou Xie, Lijun Tao, Zhaotong Wang, Yifan Tian, Lihong Wang, Feng Tang, Yijing Zheng, Xinchen Yue, Jinping Lei, Xiansong Wang, Lichen Ge, Zhuojia Chen, Hongsheng Wang   +17 more
wiley   +1 more source

Incidental Bladder Cancer Detected on Multiparametric Magnetic Resonance Imaging of the Prostate Gland [PDF]

, 2015
Al Sardari, John V. Thomas, Jeffrey W. Nix, Jason A. Pietryga, Rupan Sanyal, Jennifer Gordetsky, Soroush Rais‐Bahrami   +6 more
openalex   +1 more source

Population‐Based Multi‐Omics and Cohort Study Identifying Predictive Biomarkers and Therapeutic Targets for Psoriatic Disease

Advanced Science, EarlyView.
Psoriatic disease (PsD) is a chronic skin disease, with challenges in early risk stratification and drug development. Through gene‐level causal inference framework and expression level validation, combined with longitudinal cohort study, CDSN and PRSS8 have been identified as candidate biomarkers and therapeutic targets for PsD.
Tianxing Wu, Jialiang Luo, Haoyuan Qiu, Weijie Shao, Yueyang Lu, Meixuan Luo, Zhaofeng Lin, Yan Zhang, Libo Zhang, Hong Wang, Jia Zhou, Guangfeng Ruan, Peihua Cao, Daming Zuo   +13 more
wiley   +1 more source

Contemporary Review of Multimodality Imaging of the Prostate Gland. [PDF]

Diagnostics (Basel), 2023
Calderone CE, Turner EM, Hayek OE, Summerlin D, West JT, Rais-Bahrami S, Galgano SJ.   +6 more
europepmc   +1 more source

CD169+ Macrophage‐Targeted Immunomodulator to Restore Phagocytic Function and Enhance Antigen Presentation for Lymphatic Metastasis Eradication

Advanced Science, EarlyView.
A CD169+ macrophage‐targeted immunomodulator (G‐LNP@S‐D) is developed to co‐deliver a SHP2 inhibitor and STING agonist, thereby restoring phagocytic function, enhancing antigen presentation by CD169+ macrophages, and promoting T cell priming to eradicate lymphatic metastasis.
Xiayun Chen, Lichong Lu, Yibin Liu, Ziqi Liang, Jianqiao Li, Zhouchuan Shao, Youzhi Tang, Jianhua Zou, Shiying Li, Xiaoyuan Chen   +9 more
wiley   +1 more source

Ultrasonographic and cytopathologic aspects of prostate disease in 52 dogs [PDF]

Biotemas, 2012
This study evaluated 52 dogs, which were male, intact, varied in age, of pure or mixed breed, with clinical signs suggestive of prostatic disease. Each individual underwent an ultrasound examination and fine-needle aspiration biopsy of the prostate gland
Antonio Carlos Cunha Lacreta Junior, Márcio Botelho de Castro, Lúcia Ferreira da Rosa Sobreira, Júlio Carlos Canola   +3 more
doaj  

Active DHEA uptake in the prostate gland correlates with aggressive prostate cancer. [PDF]

J Clin Invest, 2023
Zhang X, Wang Z, Huang S, He D, Yan W, Zhuang Q, Wang Z, Wang C, Tan Q, Liu Z, Yang T, Liu Y, Ren R, Li J, Butler W, Tang H, Wei GH, Li X, Wu D, Li Z.   +19 more
europepmc   +1 more source