Results 31 to 40 of about 2,003,708 (339)

Investigating prostate cancer tumour-stroma interactions - clinical and biological insights from an evolutionary game [PDF]

open access: yes, 2011
BACKGROUND: Tumours are made up of a mixed population of different types of cells that include normal structures as well as ones associated with the malignancy, and there are multiple interactions between the malignant cells and the local ...
Alexander R. A. Anderson   +5 more
core   +3 more sources

Immunohistochemical Analysis of the Extrinsic Apoptosis Process in the Non-Neoplastic and Neoplastic Prostate

open access: yesTürk Patoloji Dergisi, 2018
Objective: Deviations in the apoptotic process have been demonstrated in prostate carcinogenesis. We aimed to evaluate especially the process of extrinsic apoptosis in the spectrum of neoplastic lesions of the prostate epithelium so as to reveal the ...
Ayşe Burcu İLERİ   +5 more
doaj   +1 more source

Histopathological study of Prostatic Lesions in a Tertiary Care Hospital, Lahore [PDF]

open access: yesJournal of Sharif Medical & Dental College, 2021
Objective: To determine the spectrum of pathological lesions seen in prostatic biopsies & to grade prostatic cancers according to the modified Gleason score & grade.
Madiha Arshad   +2 more
doaj  

Periacinar clefting and p63 immunostaining in prostatic intraepithelial neoplasia and prostatic carcinoma [PDF]

open access: yes, 2006
The aim of the present study was to correlate the presence and extent of retraction clefting and the expression of p63 in neoplastic glands and glands with prostatic intraepithelial neoplasia (PIN) in needle core biopsies.
Belicza, Mladen   +5 more
core   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

Role of cyclin D1 immunoreactivity and AgNOR staining in the evaluation of benign and malignant lesions of the prostate

open access: yesProstate International, 2014
Prostatic carcinoma is a common and growing public health problem. Histological evaluation is fairly adequate for assessing tumor differentiation, but tumor proliferative activity is difficult to measure.
Veena Gupta   +4 more
doaj   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

Primary basal cell carcinoma of the prostate with concurrent acinar adenocarcinoma and ductal adenocarcinoma: A case report and literature review

open access: yesHuman Pathology Reports, 2021
Introduction: Prostatic basal cell carcinoma (PBCC) with concurrent acinar adenocarcinoma and ductal adenocarcinoma is an extremely rare tumor that can exhibit various morphological features, as well as clinical spectrums of the disease.
Jing Yang, Peng Zhang, Min Zhang
doaj   +1 more source

Components of cell-matrix linkage as potential new markers for prostate cancer [PDF]

open access: yes, 2011
Prostate cancer is one of the most common tumor diseases worldwide. Often being non-aggressive, prostate tumors in these cases do not need immediate treatment.
Eble, Johannes Andreas, Navdaev, Alexey
core   +2 more sources

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

Home - About - Disclaimer - Privacy