Results 101 to 110 of about 1,705,126 (244)

Evolutionary Multi-Objective Design of SARS-CoV-2 Protease Inhibitor Candidates

, 2020
Computational drug design based on artificial intelligence is an emerging research area. At the time of writing this paper, the world suffers from an outbreak of the coronavirus SARS-CoV-2.
A Alhossary, CA Lipinski, CA Nicolaou, D Douguet, D Weininger, E van der Horst, E Zitzler, GR Bickerton, H Nguyen, HG Beyer, K Deb, L Zhang, N Brown, N Brown, O Trott, P Ertl, P Ertl, RF de Freitas, RV Devi, SCH Pegg, SS Kaplan, T Gaillard, T Krause, TT Wager, W Dai   +24 more
core   +1 more source

A new subfamily of fungal subtilases: structural and functional analysis of a Pleurotus ostreatus member [PDF]

, 2005
Pleurotus ostreatus produces several extracellular proteases which are believed to be involved in the regulation of the ligninolytic activities of this fungus. Recently, purification and characterization of the most abundant P.
FARACO, VINCENZA, FESTA, GIOVANNA, GIARDINA, PAOLA, MONTI, MARIA, PALMIERI G., SANNIA, GIOVANNI   +5 more
core   +2 more sources

Protease degradable electrospun fibrous hydrogels

Nature Communications, 2015
Electrospun nanofibres are promising in biomedical applications to replicate features of the natural extracellular matrix (ECM). However, nearly all electrospun scaffolds are either non-degradable or degrade hydrolytically, whereas natural ECM degrades ...
Ryan J. Wade, Ethan J Bassin, C. Rodell, J. Burdick   +3 more
semanticscholar   +1 more source

Feeding Mystus gulio Fry With Different Dietary Inclusion of Coccomyxa Sp.: Changes in Nutritional Profile, Pigments and Digestive Enzyme Activities

Aquaculture, Fish and Fisheries
The aim of this study was to investigate the effects of Coccomyxa sp. on the survival, nutritional profile, pigments and digestive enzyme activities of Mystus gulio.
Subeda Newase, Mohammad Ekramul Haque, Mahima Ranjan Acharjee, Trina Das, Sifatun Nur, Sadia Afrin, Zannatul Nayma, S. K. M. Azizul Islam, Helena Khatoon   +8 more
doaj   +1 more source

Structure, Function and Dynamics in Adenovirus Maturation

Viruses, 2014
Here we review the current knowledge on maturation of adenovirus, a non-enveloped icosahedral eukaryotic virus. The adenovirus dsDNA genome fills the capsid in complex with a large amount of histone-like viral proteins, forming the core.
Walter F. Mangel, Carmen San Martín
doaj   +1 more source

Host and bacterial proteases influence biofilm formation and virulence in a murine model of enterococcal catheter-associated urinary tract infection [PDF]

, 2017
Urinary tract infections: targeting enzymes might help Identifying bacterial and host enzymes that support biofilm formation may help prevent urinary tract infections caused by catheters.
Caparon, Michael G, Cusumano, Zachary T, Flores-Mireles, Ana L, Hultgren, Scott J, Takagi, Enzo, Xu, Wei   +5 more
core   +3 more sources

The intramembrane protease Sppl2a is required for B cell and DC development and survival via cleavage of the invariant chain

Journal of Experimental Medicine, 2013
The protease Sppl2a cleaves the N-terminal fragment of invariant chain (CD74) and is required for efficient B cell development and function.
Daniel R. Beisner, Petra Langerak, Albert E. Parker, Carol Dahlberg, Francella J. Otero, Sue E. Sutton, Laurent Poirot, Whitney Barnes, Michael A. Young, Sherry Niessen, Tim Wiltshire, Ursula Bodendorf, Bruno Martoglio, Benjamin F. Cravatt, Michael P. Cooke   +14 more
semanticscholar   +1 more source

Enzimas exógenas em dietas de frangos de corte: desempenho Exogenous enzymes in broilers fed diets: performance

Ciência Rural, 2012
O experimento foi conduzido para avaliar a eficiência de enzimas exógenas em dietas sobre o desempenho de frangos de corte. Um total de 1440 pintos de corte machos (Cobb 500®) foram distribuídos em um delineamento inteiramente casualizado em esquema ...
Nei André Arruda Barbosa, Nilva Kazue Sakomura, Melina Aparecida Bonato, Luciano Hauschild, Edgar Oviedo-Rondon   +4 more
doaj   +1 more source

Effects of Some Commercial Enzymes in the Deinking of Newsprint [PDF]

, 1972
The trend of industry, in general, today is one of recycling. This is brought about as a means of conserving our dwindling natural resources and to help abate the pollution problem.
Prickett, James O.
core   +1 more source

Protease Cleavage Leads to Formation of Mature Trimer Interface in HIV-1 Capsid [PDF]

, 2012
During retrovirus particle maturation, the assembled Gag polyprotein is cleaved by the viral protease into matrix (MA), capsid (CA), and nucleocapsid (NC) proteins.
Angela M. Gronenborn, Christopher Aiken, Danxia Ke, Ernest Yufenyuy, Gongpu Zhao, Jinwoo Ahn, Jiying Ning, John A. T. Young, Maria DeLucia, Peijun Zhang, Xin Meng   +10 more
core   +4 more sources