Results 141 to 150 of about 1,749,266 (388)

Feasibility of a ctDNA multigenic panel for non‐small‐cell lung cancer early detection and disease surveillance

open access: yesMolecular Oncology, EarlyView.
Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande   +11 more
wiley   +1 more source

Feeding Mystus gulio Fry With Different Dietary Inclusion of Coccomyxa Sp.: Changes in Nutritional Profile, Pigments and Digestive Enzyme Activities

open access: yesAquaculture, Fish and Fisheries
The aim of this study was to investigate the effects of Coccomyxa sp. on the survival, nutritional profile, pigments and digestive enzyme activities of Mystus gulio.
Subeda Newase   +8 more
doaj   +1 more source

Structure, Function and Dynamics in Adenovirus Maturation

open access: yesViruses, 2014
Here we review the current knowledge on maturation of adenovirus, a non-enveloped icosahedral eukaryotic virus. The adenovirus dsDNA genome fills the capsid in complex with a large amount of histone-like viral proteins, forming the core.
Walter F. Mangel, Carmen San Martín
doaj   +1 more source

Effects of Some Commercial Enzymes in the Deinking of Newsprint [PDF]

open access: yes, 1972
The trend of industry, in general, today is one of recycling. This is brought about as a means of conserving our dwindling natural resources and to help abate the pollution problem.
Prickett, James O.
core   +1 more source

Tumor and germline testing with next generation sequencing in epithelial ovarian cancer: a prospective paired comparison using an 18‐gene panel

open access: yesMolecular Oncology, EarlyView.
Genetic testing in epithelial ovarian cancer includes both germline and tumor‐testing. This approach often duplicates resources. The current prospective study assessed the feasibility of tumor‐first multigene testing by comparing tumor tissue with germline testing of peripheral blood using an 18‐gene NGS panel in 106 patients.
Elisabeth Spenard   +12 more
wiley   +1 more source

Enzimas exógenas em dietas de frangos de corte: desempenho Exogenous enzymes in broilers fed diets: performance

open access: yesCiência Rural, 2012
O experimento foi conduzido para avaliar a eficiência de enzimas exógenas em dietas sobre o desempenho de frangos de corte. Um total de 1440 pintos de corte machos (Cobb 500®) foram distribuídos em um delineamento inteiramente casualizado em esquema ...
Nei André Arruda Barbosa   +4 more
doaj   +1 more source

Transport of ADP/ATP carrier into mitochondria [PDF]

open access: yes, 1984
Precursor to ADP/ATP carrier synthesized in vitro is transferred into isolated mitochondria to a protease-resistant location. This process requires an electrical potential across the inner membrane.
Neupert, Walter, Schleyer, Manfred
core  

Convergent dynamics in the protease enzymatic superfamily

open access: yes, 2006
Proteases regulate various aspects of the life cycle in all organisms by cleaving specific peptide bonds. Their action is so central for biochemical processes that at least 2% of any known genome encodes for proteolytic enzymes.
Carloni, Paolo   +3 more
core   +1 more source

Bcl-2 inhibits the mitochondrial release of an apoptogenic protease

open access: yesJournal of Experimental Medicine, 1996
Bcl-2 belongs to a family of apoptosis-regulatory proteins which incorporate into the outer mitochondrial as well as nuclear membranes. The mechanism by which the proto-oncogene product Bcl-2 inhibits apoptosis is thus far elusive.
S. Susin   +8 more
semanticscholar   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

open access: yesMolecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang   +8 more
wiley   +1 more source

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