Results 201 to 210 of about 695,446 (323)

Effects of protease inhibitors in experimental septic shock [PDF]

, 1992
Fink, Edwin, Hoffmann, H., Siebeck, Matthias, Spannagl, Michael   +3 more
core  

Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment

Aging and Cancer, EarlyView.
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey, Murilo Ramos Rocha, Cheyenne Palm, Vania Wang, Denys Balandin, Ethan Black, Kevin Y. Zhang, Fan Huang, Daniel J. Zabransky, Yash Chhabra, Mareike Peters, Gabriel Ghiaur, Ashani Weeraratna   +12 more
wiley   +1 more source

Correction: Discovery of protease inhibitors from bacteria as novel adjuvants for oral vaccine formulations. [PDF]

Front Immunol
Coria LM, Pueblas Castro C, Bruno L, Nakaya HI, Pasquevich KA, Cassataro J.   +5 more
europepmc   +1 more source

The Aging Blood: Cellular Origins, Circulating Drivers, and Therapeutic Potential

Aging and Cancer, EarlyView.
As a conduit linking all organs, the blood system both reflects and actively drives systemic aging. This review highlights how circulating pro‐aging and antiaging factors and age‐associated hematopoietic stem cell dysfunction contribute to immunosenescence and multi‐organ decline, positioning the hematopoietic system as a target for aging intervention.
Hanqing He, Jianwei Wang
wiley   +1 more source

Co-cultivation and Medium Optimization: A Strategy for Discovering Fungal-derived Protease Inhibitors. [PDF]

Chem Biodivers
Mazucato VS, Tonani L, von Zeska Kress MR, Andricopulo AD, Barbosa G, Krogh R, Gomes Ferreira LL, Vieira PC.   +7 more
europepmc   +1 more source

Therapeutic Opportunities in Infectious Diseases: Highlights from the Society of Medicines Research Symposium, held on March 14th 2013 at the National Heart & Lung Institute, London, UK [PDF]

, 2013
Alderton, W K, Anderson, Rosaleen, Collingwood, S P, Pryde, D C   +3 more
core   +1 more source

Quantitative SNP‐Detection Method for Estimating HIV‐1 Replicative Fitness: Application to Protease Inhibitor‐Resistant Viruses [PDF]

, 2006
Shiro Ibe, Saeko Fujisaki, Seiichiro Fujisaki, Takayuki Morishita, Tsuguhiro Kaneda   +4 more
openalex   +1 more source

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

Aging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu, Latif Adams, Eunice Ampem‐Danso, Justice Kumi, Abigail Aning, Fatima Hamidu, Mustapha Abdul Mumin Mohammed, Ayuba Nii Darku Ankrah, Seth Kwabena Amponsah   +8 more
wiley   +1 more source

Kazal-type serine protease inhibitors from Arabidopsis thaliana and Toxoplasma gondii exhibit antimicrobial activity against plant pathogens. [PDF]

Sci Rep
Sánchez MA, Strack KN, Mendoza-Morales LF, Ramos-Duarte VA, Pérez Sanchidrian E, Sander VA, Melina LB, Pieckenstain FL, Clemente M.   +8 more
europepmc   +1 more source

Vaccinia Virus Encodes Two Proteins That Are Structurally Related to Members of the Plasma Serine Protease Inhibitor Superfamily [PDF]

, 1990

openalex   +1 more source