Results 201 to 210 of about 3,573,509 (380)

Primary structural analysis of sulfhydryl protease inhibitors from pineapple stem.

, 1975
M N Reddy, P S Keim, Robert L. Heinrikson, Ferenc J. Kézdy   +3 more
openalex   +1 more source

Photothermal Hydrogel with Mn3O4 Nanoparticles Alleviates Intervertebral Disc Degeneration by Scavenging ROS and Regulating Extracellular Matrix Metabolism

Advanced Functional Materials, EarlyView.
The MPTT‐nanozyme‐hydrogel system (Mn3O4@ChS‐HA) provides a multifunctional therapeutic strategy for intervertebral disc degeneration (IVDD), effectively targeting oxidative stress and enhancing AF repair by restoring extracellular matrix (ECM) and redox homeostasis.
Yangyang Chen, Chan Xue, Feifei Ni, Binwu Hu, Miaoheng Yan, He Zhang, Yuxiang Hu, Xiaoyao Peng, Guangfang Li, Yu Han, Hongjian Liu, Zengwu Shao, Qin Wang, Yulong Wei   +13 more
wiley   +1 more source

Alleviation of Aging‐Related Hallmarks in a Mouse Model of Progeria via a Nanoparticle‐Based Artificial Transcription Factor

Advanced Functional Materials, EarlyView.
Oct4‐nanoscript, a biomimetic nanoparticle‐based artificial transcription factor, precisely regulates cellular rejuvenation by activating Oct4 target genes, restoring epigenetic marks, and reducing DNA damage. In a progeria model, it effectively rescued aging‐associated pathologies and extended lifespan.
Hongwon Kim, Junyeop Kim, Euiyeon Lee, Brandon Conklin, Yannan Hou, Sumin Kim, Yerim Hwang, Ki‐Bum Lee, Jongpil Kim   +8 more
wiley   +1 more source

Protease Inhibitors and their Relation to Protease Activity in Human Milk [PDF]

, 1982
Tor Lindberg, Hindrik Mulder, Björn Weström   +2 more
openalex   +1 more source

Intraoral Drug Delivery: Bridging the Gap Between Academic Research and Industrial Innovations

Advanced Functional Materials, EarlyView.
Intraoral drug delivery offers a promising route for systemic and localized therapies, yet challenges such as enzymatic degradation, limited permeability, and microbial interactions hinder efficacy. This figure highlights innovative strategies—mucoadhesive materials, enzyme inhibitors, and permeation enhancers—to overcome these barriers.
Soheil Haddadzadegan, Simona Summonte, Fabrizio Ricci, Matthias Sandmeier, Andreas Bernkop‐Schnürch   +4 more
wiley   +1 more source

Formation of a stable complex between human proelastase 2 and human alpha 1-protease inhibitor.

, 1979
Corey Largman, James W. Brodrick, Michael C. Geokas, William M. Sischo, J.H. Johnson   +4 more
openalex   +1 more source

Localisation of a low-molecular-weight bronchial protease inhibitor in the peripheral human lung. [PDF]

, 1983
H.W.D. Mooren, J. A. Kramps, C Franken, C J Meijer, J A Dijkman   +4 more
openalex   +1 more source

Machine Learning‐Enabled Polymer Discovery for Enhanced Pulmonary siRNA Delivery

Advanced Functional Materials, EarlyView.
This study provides an efficient approach to train a machine learning model by merging heterogeneous literature data to predict suitable polymers for siRNA delivery. Without the need for extensive laboratory synthesis, the machine learning enabled a virtual screening and successfully predicted a polymer that is validated for effective gene silencing in
Felix Sieber‐Schäfer, Min Jiang, Adrian Kromer, Anny Nguyen, Müge Molbay, Simone Pinto Carneiro, David Jürgens, Gerald Burgstaller, Bastian Popper, Benjamin Winkeljann, Olivia Monika Merkel   +10 more
wiley   +1 more source

HIV protease inhibitors restore amphotericin B activity against Candida. [PDF]

PLoS One
Elgammal Y, Salama EA, Seleem MN.
europepmc   +1 more source

Novel microbial alkaline protease inhibitor, MAPI, produced by Streptomyces sp. No. WT-27.

, 1977
Sawao Murao, Takashi Watanabe
openalex   +2 more sources