Results 271 to 280 of about 4,152,860 (338)

Magnetic Micro‐ and Nanorobots for Precision Thrombolysis: Design Strategies and Translational Challenges

Advanced Robotics Research, EarlyView.
Micro‐ and nanorobots for targeted thrombolysis. This perspective elaborates on the clinical indication of blood clot disorders and current limitations for treatment. As a novel, alternative solution, micro‐ and nanorobots can be used to treat and break down thrombi.
Joshua M. Mesfin, Yimo Yan, Nikola Cesarovic, Simone Schuerle   +3 more
wiley   +1 more source

Computational identification of aspartic protease inhibitors for antimalarial drug development against Plasmodium Vivax. [PDF]

Sci Rep
Alruwaili M, Alhassan HH, Almutary H, Tahir Ul Qamar M.   +3 more
europepmc   +1 more source

Pretreatment with serine protease inhibitors impairs Leishmania amazonensis survival on macrophages. [PDF]

Parasit Vectors
de Almeida Machado P, Gomes PS, Coimbra ES, de Matos Guedes HL.   +3 more
europepmc   +1 more source

<i><b>N</b></i>-Alkyl Sulfamates as a New Class of nsP2 Cysteine Protease Inhibitors with Broad-Spectrum Antialphaviral Activity. [PDF]

J Med Chem
Ghoshal A, Sears JD, Hossain MA, Tse EG, Howell S, Burdick JE, Morales NL, Martinez SA, Law I, Streblow ZJ, Streblow DN, Couñago RM, Moorman NJ, Heise MT, Willson TM.   +14 more
europepmc   +1 more source

Using protease inhibitors to prevent intraperitoneal adhesions: effects of nafamostat mesylate, UAMC-00050, GM6001, and enoxaparin in the cecal ligation and puncture model and the ischemic button model. [PDF]

Surg Today
Plaeke P, De Man J, Hong GS, de Bruyn M, De Meester I, Jorens PG, Augustyns K, Kalff JC, Wehner S, Hubens G, De Winter B.   +10 more
europepmc   +1 more source

Host-Directed Therapies Based on Protease Inhibitors to Control <i>Mycobacterium tuberculosis</i> and HIV Coinfection. [PDF]

Microorganisms
Mandal M, Pires D, Azevedo-Pereira JM, Anes E.   +3 more
europepmc   +1 more source

Corrigendum to "Serine protease inhibitors could be of benefit in the treatment of COVID-19 disease". [PDF]

Ther Adv Infect Dis
europepmc   +1 more source

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HIV-Protease Inhibitors

New England Journal of Medicine, 1998
Inhibitors of human immunodeficiency virus (HIV)–encoded protease, combined with nucleoside analogues with antiretroviral activity, cause profound and sustained suppression of viral replication, reduce morbidity, and prolong life in patients with HIV infection.1–3 Recent guidelines recommend that initial treatment of all HIV-infected patients include ...
Charles W Flexner
openaire   +4 more sources

Bacterial protease inhibitors

Medicinal Research Reviews, 2002
AbstractSerine‐, cysteine‐, and metalloproteases are widely spread in many pathogenic bacteria, where they play critical functions related to colonization and evasion of host immune defenses, acquisition of nutrients for growth and proliferation, facilitation of dissemination, or tissue damage during infection. Since all the antibiotics used clinically
SUPURAN, CLAUDIU TRANDAFIR, SCOZZAFAVA, ANDREA, B. W. Clare   +2 more
openaire   +3 more sources