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Modulation of Campylobacter jejuni adhesion to biotic model surfaces by fungal lectins and protease inhibitors. [PDF]
Front Cell Infect MicrobiolJug B +8 more
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Change in Blood Pressure, Weight, and Other Cardiovascular Disease Risk Factors After Switch From Protease Inhibitors to Dolutegravir: Post hoc Analysis of the 48-week Randomised Second-line Switch to Dolutegravir Trial. [PDF]
Clin Infect DisOmbajo LA +7 more
europepmc +1 more source
Investigating tissue factor pathway inhibitor and other protease and protease inhibitors and their association with major adverse aortic events in patients with abdominal aortic aneurysm. [PDF]
Res Pract Thromb HaemostKhan H +5 more
europepmc +1 more source
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Proteases and protease inhibitors in infectious diseases
Medicinal Research Reviews, 2018AbstractThere are numerous proteases of pathogenic organisms that are currently targeted for therapeutic intervention along with many that are seen as potential drug targets. This review discusses the chemical and biological makeup of some key druggable proteases expressed by the five major classes of disease causing agents, namely bacteria, viruses ...
A. A. Agbowuro +3 more
semanticscholar +4 more sources
Journal of Biomolecular Structure and Dynamics, 2020
Recently, the world has witnessed outbreak of a novel Coronavirus (SARS-CoV-2), the virus which initially emerged in Wuhan, China has now made its way to a large part of the world, resulting in a public emergency of international concern.
S. Khan +4 more
semanticscholar +1 more source
Recently, the world has witnessed outbreak of a novel Coronavirus (SARS-CoV-2), the virus which initially emerged in Wuhan, China has now made its way to a large part of the world, resulting in a public emergency of international concern.
S. Khan +4 more
semanticscholar +1 more source
Protease Inhibitors in the Clinic
Medicinal Chemistry, 2005This review describes the clinical status (based on available information) of experimental drugs that inhibit enzymes called proteases, or more precisely a sub-class of proteases called peptidases that catalyse the hydrolysis of polypeptide main chain amide bonds.
Abbenante, Giovanni, Fairlie , David P.
openaire +4 more sources
Medicinal Research Reviews, 2002
AbstractSerine‐, cysteine‐, and metalloproteases are widely spread in many pathogenic bacteria, where they play critical functions related to colonization and evasion of host immune defenses, acquisition of nutrients for growth and proliferation, facilitation of dissemination, or tissue damage during infection. Since all the antibiotics used clinically
SUPURAN, CLAUDIU TRANDAFIR +2 more
openaire +4 more sources
AbstractSerine‐, cysteine‐, and metalloproteases are widely spread in many pathogenic bacteria, where they play critical functions related to colonization and evasion of host immune defenses, acquisition of nutrients for growth and proliferation, facilitation of dissemination, or tissue damage during infection. Since all the antibiotics used clinically
SUPURAN, CLAUDIU TRANDAFIR +2 more
openaire +4 more sources