The Interleukin-1 Receptor-associated Kinase Is Degraded by Proteasomes following Its Phosphorylation [PDF]
Ting-Ting Yamin, Douglas K. Miller
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Solving the Amyloid Paradox: Unveiling the Complex Pathogenicity of Amyloid Fibrils
This review addresses the gap between strong evidence for the involvement of amyloid fibrils in neurodegeneration and the failure of anti‐amyloid therapies, a phenomenon herein termed the “amyloid paradox.” To address this paradox, we provide a comprehensive summary of the current understanding of fibrils' pathogenic properties and mechanisms ...
Maksim I. Sulatsky+3 more
wiley +1 more source
Suppressing proteasome activity enhances sensitivity to actinomycin D in diffuse anaplastic Wilms tumor. [PDF]
Tiburcio PDB, Chen K, Xu L, Chen KS.
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The COP9 complex is conserved between plants and mammals and is related to the 26S proteasome regulatory complex [PDF]
Ning Wei+6 more
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Harnessing the Biological Responses Induced by Nanomaterials for Enhanced Cancer Therapy
Nanomaterial (NM)‐induced toxicity can be strategically repurposed for cancer therapy. This review summarizes the mechanism by which NMs selectively activate specific cellular processes to regulate cell fate independently. We also discussed how NMs‐induced biological responses can be leveraged as therapeutic strategies for cancer treatment.
Liting Wang+6 more
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Extracellular Vesicle-Mediated Delivery of 20S Proteasomes Enhances Tau Degradation in Recipient Cells. [PDF]
Kim J+5 more
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ABSTRACT Disease Overview Primary cutaneous lymphomas are a rare and heterogeneous group of extranodal lymphomas that require the integration of clinical and histopathologic data for classification and treatment. Diagnosis Diagnosis and disease classification is based on histopathologic review and immunohistochemical staining of an appropriate skin ...
Alexandra C. Hristov+2 more
wiley +1 more source
Multifaceted investigations of PSMB8 provides insights into prognostic prediction and immunological target in thyroid carcinoma. [PDF]
Luo Y+4 more
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HslV-HslU: A novel ATP-dependent protease complex in Escherichia coli related to the eukaryotic proteasome. [PDF]
Markus Rohrwild+7 more
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Current trends and future prospects of N-acetylcysteine utilizations in Parkinson's disease: A literature network analysis. [PDF]
Muthmainah M+5 more
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