Results 291 to 300 of about 355,945 (323)

Hypoxia Increases Cardiac Proteasomal Activity and Differentially Modulates Cullin-RING E3 Ligases in the Naked Mole-Rat <i>Heterocephalus glaber</i>. [PDF]

Muscles
Ingelson-Filpula WA, Kadamani KL, Ojaghi M, Pamenter ME, Storey KB.   +4 more
europepmc   +1 more source

Understanding Neurodegenerative Diseases From the −Omics Perspective: Lessons Learnt

Annals of Neurology, EarlyView.
As the population ages, certain neurodegenerative diseases (NDs) are becoming a major health issue. For this reason, this review will focus on the most common ND with onset after 65 years old; Alzheimer's disease, Parkinson's disease, Lewy body dementia, and frontotemporal dementia.
Laura Ibanez, Cyril Pottier, Aleksandra Beric, Daniel Western, Muhammad Ali, Carlos Cruchaga   +5 more
wiley   +1 more source

The dual role of the ubiquitin-proteasome system in photomorphogenesis. [PDF]

Essays Biochem
Zhou H, Deng XW.
europepmc   +1 more source

Examination of sodium arsenite- and cadmium chloride-induced HSP accumulation and inhibition of proteasome activity in Xenopus laevis A6 kidney epithelial cells

, 2011
Jara J. Brunt
openalex   +1 more source

Safety, tolerability and pharmacokinetics of DNDI‐6148, a novel agent for leishmaniasis: A randomized, controlled, single ascending dose study in healthy participants

British Journal of Clinical Pharmacology, EarlyView.
Aim The benzoxaborole derivative DNDI‐6148 is an antiparasitic agent with activity against multiple Leishmania protozoan species, including L. infantum and L. donovani, which cause visceral leishmaniasis. We investigated the safety, tolerability and pharmacokinetics of single oral doses of DNDI‐6148 in a randomized, parallel‐group, placebo‐controlled ...
Jean‐Yves Gillon, Sophie Delhomme, Delphine Launay, Séverine Blesson, Stéphanie Braillard, Pegah Maghdooni, Frauke Assmus, Richard Hoglund, Joel Tarning, Sabrina Loyau, Byron Arana, Mathilde Latreille‐Barbier, Yves Donazzolo   +12 more
wiley   +1 more source

Role of p62 nuclear condensates in regulating ubiquitin-mediated proteasomal degradation. [PDF]

Essays Biochem
Lulu-Shimron C, Ciechanover A, Cohen-Kaplan V.   +2 more
europepmc   +1 more source

HBV Infection Drives PSMB5-Dependent Proteasomal Activation in Humanized Mice and HBV-Associated HCC. [PDF]

Viruses
Jannuzzi AT, Sari G, Arslan-Eseryel S, Zeybel M, Yilmaz Y, Dayangac M, Yigit B, Arga KY, Boonstra A, Eren F, Karademir-Yilmaz B.   +10 more
europepmc   +1 more source

Pharmacological inhibition of host pathways enhances macrophage killing of intracellular bacterial pathogens. [PDF]

Microbiol Spectr
Rijal R, Gomer RH.
europepmc   +1 more source

Harnessing Ubiquitin-Proteasome System-Related Genes to Identify Subtypes of Bladder Cancer and Reveal Immune Landscape. [PDF]

Am J Mens Health
Shi G, Zhou X, Yang F, Wang T.
europepmc   +1 more source