Results 221 to 230 of about 3,106,146 (396)

Editorial expression of concern (EEoC): small interfering RNA targeting mcl-1 enhances proteasome inhibitor-induced apoptosis in various solid malignant tumors. [PDF]

BMC Cancer
Zhou W, Hu J, Tang H, Wang D, Huang X, He C, Zhu H.   +6 more
europepmc   +1 more source

Natural Negative Feedback Loops Confer Indica‐Japonica Differentiation for Grain Size Homeostasis in Rice

Advanced Science, EarlyView.
This study reveals the genetic and molecular mechanisms controlling grain size homeostasis through fine‐tuning OsGRX8 self‐expression by two natural negative feedback loops functioning in redox‐dependent or ‐independent manners and identifies two self‐regulatory haplotypes (SRHs) for the subspecies differentiation in rice.
Xingxing Li, Meng‐en Wu, Ziqi Qiao, Junkui Huang, Juncheng Zhang, Yang Ding, Junqing Zhu, Jingyue Xu, Yuxin Huang, Wei Li, Xiaomin Su, Yue Ding, Jianwei Zhang, Yibo Li   +13 more
wiley   +1 more source

[Corrigendum] Dual targeting of glioblastoma multiforme with a proteasome inhibitor (Velcade) and a phosphatidylinositol 3‑kinase inhibitor (ZSTK474). [PDF]

Int J Oncol
Lin L, Gaut D, Hu K, Yan H, Yin D, Koeffler PH.   +5 more
europepmc   +1 more source

Metabolic Alterations in Multiple Myeloma: From Oncogenesis to Proteasome Inhibitor Resistance. [PDF]

Cancers (Basel), 2023
Weir P, Donaldson D, McMullin MF, Crawford L.   +3 more
europepmc   +1 more source

OTUD6A in Airway Epithelial Cells Exacerbates Allergic Asthma by Promoting Airway Inflammation and Airway Remodeling Through Deubiquitination of hResistin/mRELMα

Advanced Science, EarlyView.
This study elucidates a novel mechanistic role of the deubiquitinase OTUD6A in asthma pathogenesis, uncovering its regulatory function in airway inflammation and airway remodeling through the stabilization of hResistin/mRELMα. This study offers a novel regulatory axis (OTUD6A‐hResistin/mRELMα) in asthma pathogenesis and OTUD6A inhibition as a potential
Weiting Pan, Xinru Xi, Wei Dai, Tingfang Xiao, Yeqing Chen, Xuanyu Chen, Xiangting Ge, Chengguang Zhao, Hui Zhang, Yali Zhang, Weixi Zhang   +10 more
wiley   +1 more source

991 Comparative study of the skin lesions of Nakajo-Nishimura syndrome and PSMB9-related autoinflammatory syndrome with cutaneous adverse reactions by a proteasome inhibitor [PDF]

, 2018
Kayo Kunimoto, Yutaka Inaba, Noriko Kinjo, Akira Kinoshita, Ko‐ichiro Yoshiura, Masatoshi Jinnin, Nobuo Kanazawa   +6 more
openalex   +1 more source

Proteostasis Disruption by Proteasome Inhibitor MG132 and Propolin G Induces ER Stress- and Autophagy-Mediated Apoptosis in Breast Cancer. [PDF]

Food Sci Nutr
Pai JT, Chen LP, Chang HJ, Wang SW, Leu YL, Lai CT, Weng MS.   +6 more
europepmc   +1 more source

[Retracted] Proteasome inhibitor sensitizes oral squamous cell carcinoma cells to TRAIL‑mediated apoptosis. [PDF]

Oncol Rep, 2023
Yoshiba S, Iwase M, Kurihara S, Uchida M, Kurihara Y, Watanabe H, Shintani S.   +6 more
europepmc   +1 more source

Pirin Transcriptionally Regulates PLA2G4A To Inhibit Ferroptosis in Colorectal Cancer via Lipid Profile Remodeling

Advanced Science, EarlyView.
This study identifies Pirin (PIR), an iron‐binding protein, as a critical ferroptosis suppressor in colorectal cancer through lipid membrane remodeling. PIR, induced by NRF2 during ferroptotic stress, transcriptionally regulates PLA2G4A to shift cellular lipid composition away from ferroptosis‐permissive polyunsaturated phospholipids.
Wei Shi, Yue Qi Ong, Prativa Majee, Esther SM Wong, Amhed Missael Vargas Velazquez, Kerem Fidan, Pierce Kah‐Hoe Chow, Wai Leong Tam, Ker Kan Tan, Iain Beehuat Tan, Vinay Tergaonkar   +10 more
wiley   +1 more source

Multiple cardiac proteasome subtypes differ in their susceptibility to proteasome inhibitors [PDF]

, 2009
Alexander Kloß, Silke Meiners, Antje Ludwig, Burkhardt Dahlmann   +3 more
openalex   +1 more source