Results 121 to 130 of about 436,780 (305)

The inbreeding paradox: Is inbreeding avoidance inevitable? - A case study of moose (Alces alces) in the Northeast China

open access: yesGlobal Ecology and Conservation
Genetic diversity is key for species’ resistance (enabling them to endure disturbances with little alteration) and resilience (recovering swiftly to their original state or a similar condition).
Lu Jin   +5 more
doaj   +1 more source

Suppression of lung adenocarcinoma migration through organelle alkalization by human lactoferrin – albumin fusion

open access: yesFEBS Open Bio, EarlyView.
This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia   +3 more
wiley   +1 more source

The Premium of Marine Protected Areas: A Simple Valuation Model [PDF]

open access: yes
The article addresses the induced cost, the premium, from establishing a marine protected area in a deterministic model of a fishery. Outside the protected area, the fishery is managed optimally through total allowable catch quotas.
Kvamsdal, Sturla Furunes   +1 more
core   +1 more source

Eco-epidemiological mechanisms of avian influenza and Newcastle virus co-infection: Spatial convergence and compatibility

open access: yesPoultry Science
Understanding the mechanisms of viral co-infection in natural host populations is crucial for predicting pathogen dynamics and cross-species transmission risks.
Sipei Zhang   +14 more
doaj   +1 more source

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

open access: yesFEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho   +4 more
wiley   +1 more source

Australian experiences in strategic frameworks for visitor management [PDF]

open access: yes, 2010
Australia has been applying strategic frameworks for visitor management since the 1980s. There are at least 20 examples of planning frameworks (e.g. Recreation Opportunity Spectrum, Limits of Acceptable Change) being used in this country.
Moore, S.A.
core   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

open access: yesFEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero   +5 more
wiley   +1 more source

Bioeconomic analysis of protected area use in fisheries management [PDF]

open access: yes
Protected areas in fishery management have been suggested to hedge management failures and variation in harvests. In this paper, a stochastic bioeconomic model of a two-species fishery in the Manning Bioregion is used to test the performance of protected
Greenville, Jared W.   +1 more
core   +1 more source

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

open access: yesFEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour   +2 more
wiley   +1 more source

Marine Protected Areas in Fisheries Management [PDF]

open access: yes
The use of protected areas as a fishery management tool has been suggested as a hedge against management failures and variation in harvests. A stochastic bioeconomic model of a two-species fishery will be used to test the performance of protected areas ...
Greenville, Jared W.   +1 more
core   +1 more source

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