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Hair follicle stem cells: Walking the maze

European Journal of Cell Biology, 2007
The discovery of epithelial stem cells (eSCs) in the bulge region of the outer root sheath of hair follicles in mice and man has encouraged research into utilizing the hair follicle as a therapeutic source of stem cells (SCs) for regenerative medicine, and has called attention to the hair follicle as a highly instructive model system for SC biology ...
Ralf Paus, Sanjay Tiwari, Stephan Tiede   +2 more
exaly   +5 more sources

Hair Follicle Stem Cells [PDF]

Journal of Investigative Dermatology Symposium Proceedings, 2003
The workshop on Hair Follicle Stem Cells brought together investigators who have used a variety of approaches to try to understand the biology of follicular epithelial stem cells, and the role that these cells play in regulating the hair cycle.
Lavker, Robert M, Sun, Tung-Tien, Oshima, Hideo, Barrandon, Yann, Akiyama, Masashi, Ferraris, Corinne, Chevalier, Genevieve, Favier, Bertrand, Jahoda, Colin a B, Dhouailly, Danielle, Panteleyev, Andrei A, Christiano, Angela M   +11 more
openaire   +6 more sources

Hair Follicle Stem Cell Isolation and Expansion

Bio-Protocol, 2018
Stem cells are widely used for numerous clinical applications including limbal stem cell deficiency. Stem cell derived from the bulge region of the hair follicle have the ability to differentiate into a variety of cell types including interfollicular ...
Mindy Call, Ewa Meyer, Winston Kao, Friedrich Kruse, Ursula Schloetzer-Schredhardt   +4 more
doaj   +4 more sources

Hair Graying Regulators Beyond Hair Follicle

Frontiers in Physiology, 2022
Hair graying is an interesting physiological alteration associated with aging and certain diseases. The occurrence is due to depigmentation of the hair caused by depletion and dysfunction of melanocyte stem cells (MeSCs).
Jing Chen, Jing Chen, Yixin Zheng, Chen Hu, Xuexiao Jin, Xiaoping Chen, Ying Xiao, Chaochen Wang, Chaochen Wang   +8 more
doaj   +1 more source

Epidermal Stem Cells in Hair Follicle Cycling and Skin Regeneration: A View From the Perspective of Inflammation

Frontiers in Cell and Developmental Biology, 2020
There are many studies devoted to the role of hair follicle stem cells in wound healing as well as in follicle self-restoration. At the same time, the influence of the inflammatory cells on the hair follicle cycling in both injured and intact skin is ...
Elena I. Morgun, Ekaterina A. Vorotelyak
doaj   +1 more source

Expression of mesenchymal stem cell marker CD90 on dermal sheath cells of the anagen hair follicle in canine species

European Journal of Histochemistry, 2009
The dermal sheath (DS) of the hair follicle is comprised by fibroblast-like cells and extends along the follicular epithelium, from the bulb up to the infundibulum.
A.M. Gargiulo, V. Pedini, C. Dall’Aglio, P. Ceccarelli, L. Pascucci, F. Mercati   +5 more
doaj   +3 more sources

Signaling pathways in hair aging

Frontiers in Cell and Developmental Biology, 2023
Hair follicle (HF) homeostasis is regulated by various signaling pathways. Disruption of such homeostasis leads to HF disorders, such as alopecia, pigment loss, and hair aging, which is causing severe health problems and aesthetic concerns.
Aishi Liang, Yingshan Fang, Lan Ye, Jianda Meng, Xusheng Wang, Jinsong Chen, Xuejuan Xu   +6 more
doaj   +1 more source

miR-149-5p Regulates Goat Hair Follicle Stem Cell Proliferation and Apoptosis by Targeting the CMTM3/AR Axis During Superior-Quality Brush Hair Formation

Frontiers in Genetics, 2020
The Yangtze River Delta white goat is a unique goat species that can produce superior quality brush hair. CKLF-like MARVEL transmembrane domain-containing 3 (CMTM3), which influences the transcriptional activity of androgen receptor (AR), was identified ...
Jian Wang, Jian Wang, Jingwen Qu, Yongjun Li, Yongjun Li, Yunkui Feng, Jinliang Ma, Liuming Zhang, Changjiang Chu, Huiru Hu, Yanhu Wang, Dejun Ji   +11 more
doaj   +1 more source

SnapShot: Hair Follicle Stem Cells

Cell, 2011
The hair follicle is an outstanding model for dissecting the biology of vertebrate stem cells. This SnapShot illustrates the current understanding of key aspects of hair follicle stem cell development and homeostasis.
Woo, Wei-Meng, Oro, Anthony E.
openaire   +2 more sources

LGR5 is a conserved marker of hair follicle stem cells in multiple species and is present early and throughout follicle morphogenesis

Scientific Reports, 2022
Hair follicle stem cells are key for driving growth and homeostasis of the hair follicle niche, have remarkable regenerative capacity throughout hair cycling, and display fate plasticity during cutaneous wound healing.
Kathryn M. Polkoff, Nithin K. Gupta, Adrian J. Green, Yanet Murphy, Jaewook Chung, Katherine L. Gleason, Sean G. Simpson, Derek M. Walker, Bruce Collins, Jorge A. Piedrahita   +9 more
doaj   +1 more source