Results 11 to 20 of about 5,121,563 (149)
CellsHair follicle (HF) stem cells are multipotent adult stem cells that play a key role in the hair follicle cycle. However, it remains poorly understood how the outer root sheath (ORS)—specifically, the stem cells in the bulge region of the hair follicle ...
Hangzhen Zhou +4 more
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Thyroxine differentially modulates the peripheral clock: lessons from the human hair follicle [PDF]
, 2015 The human hair follicle (HF) exhibits peripheral clock activity, with knock-down of clock genes (BMAL1 and PER1) prolonging active hair growth (anagen) and increasing pigmentation.
Haslam, Iain S. +16 more
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The Pluripotency of Hair Follicle Stem Cells [PDF]
Cell Cycle, 2005 The hair follicle bulge area is an abundant, easily accessible source of actively growing, pluripotent adult stem cells. Nestin, a protein marker for neural stem cells, is also expressed in follicle stem cells as well as their immediate differentiated progeny.
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T-Regulating Hair Follicle Stem Cells [PDF]
Immunity, 2017 Regulatory T (Treg) cells are well known to modulate inflammatory responses. In a recent issue of Cell, Ali et al. (2017) reveal a function for Treg cells in stem cell maintenance by showing that skin-resident Foxp3+ Treg cells preferentially localize to the hair follicle stem cell (HFSC) niche to control HFSC-mediated hair regeneration.
Maria, Maryanovich, Paul S, Frenette
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Journal of Mazandaran University of Medical Sciences, 2022 Hair loss is a common hair disorder in human population. It affects quality of life and there are ongoing attempts to find permanent treatment for this condition. But, today there is no completely safe and protective treatment for all. Hair follicle stem
Razieh Zarei +2 more
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Scientific Reports, 2022 Stimulation of hair growth in hair loss has been a difficult goal to achieve. Hair follicle-associated pluripotent (HAP) stem cells express nestin and have been shown to differentiate to multiple cell types including keratinocytes, neurons, beating ...
Koya Obara +7 more
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Hair Follicles, Stem Cells, and Skin Cancer.
Journal of Investigative Dermatology, 1993 Abbreviations: BCC, basal cell carcinoma; BP, benzo(a)pyrene; DMBA, 7,12-dimethylbenz(a)anthracene; LRCs, label-retaining cells; MCA, 3-methylcholanthrene; SCC, squamous cell carcinoma; TdR, [3H]thymidine; TPA, 12-O-tetradecanoylphorbol-13 ...
Miller, Stanley J. +2 more
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eLife, 2015 Long-term adult stem cells sustain tissue regeneration throughout the lifetime of an organism. They were hypothesized to originate from embryonic progenitor cells that acquire long-term self-renewal ability and multipotency at the end of organogenesis ...
Zijian Xu +7 more
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Stem cell dynamics in the hair follicle niche [PDF]
Seminars in Cell & Developmental Biology, 2014 Hair follicles are appendages of the mammalian skin that have the ability to periodically and stereotypically regenerate in order to continuously produce new hair over our lifetime. The ability of the hair follicle to regenerate is due to the presence of stem cells that along with other cell populations and non-cellular components, including molecular ...
Panteleimon, Rompolas, Valentina, Greco
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Aging of hair follicle stem cells and their niches
BMB Reports, 2022 Hair follicles in the skin undergo cyclic rounds of regeneration, degeneration, and rest throughout life. Stem cells residing in hair follicles play a pivotal role in maintaining tissue homeostasis and hair growth cycles. Research on hair follicle aging and age-related hair loss has demonstrated that a decline in hair follicle stem cell (HFSC) activity
Hansaem Jang +3 more
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