Results 41 to 50 of about 5,121,563 (149)

-methyladenosine (mA)-circHECA facilitates the differentiation of SHF stem cells into hair follicle lineage through miR-449a-5p/LEF1 mediated Wnt/β-catenin pathway in cashmere goats [PDF]

Animal Bioscience
Objective This study investigates the potential effect of N6-methyladenosine (m6A)-circHECA on the differentiation of SHF stem cells into hair follicle lineage along with the underlying molecular mechanisms in cashmere goats.
Yixing Fan, Taiyu Hui, Qi Zhang, Ruqing Xu, Jincheng Shen, Yubo Zhu, Man Bai, Wenlin Bai   +7 more
doaj   +1 more source

MCL‑1 safeguards activated hair follicle stem cells to enable adult hair regeneration

Nature Communications
Hair follicles cycle through expansion, regression and quiescence. To investigate the role of MCL‑1, a BCL‑2 family protein with anti‑apoptotic and apoptosis‑unrelated functions, we delete Mcl‑1 within the skin epithelium using constitutive and inducible
Hui San Chin, Jinming Cheng, Shih Han Hsu, Guo Guang Lum, Maria TK Zaldivia, Sarmilla Nelameham, Fusheng Guo, Keerthana Mallavarapu, Felicity C. Jackling, Jicheng Yang, Jonathan S. L. Tan, Prabha Sampath, Nick Barker, Gordon K. Smyth, Geoffrey J. Lindeman, Andreas Strasser, Jane E. Visvader, Yunshun Chen, Ting Chen, Nai Yang Fu   +19 more
doaj   +1 more source

Pre-aggregation of scalp progenitor dermal and epidermal stem cells activates the WNT pathway and promotes hair follicle formation in in vitro and in vivo systems

Stem Cell Research & Therapy, 2019
Background Billions of dollars are invested annually by pharmaceutical companies in search of new options for treating hair loss conditions; nevertheless, the challenge remains.
Yiqun Su, Jie Wen, Junrong Zhu, Zhiwei Xie, Chang Liu, Chuan Ma, Qun Zhang, Xin Xu, Xunwei Wu   +8 more
doaj   +1 more source

Fisetin Promotes Hair Growth by Augmenting TERT Expression

Frontiers in Cell and Developmental Biology, 2020
Although thinning hair and alopecia are not recognized as severe diseases, hair loss has implications for mental health and quality of life; therefore, a large number of studies have been carried out to develop novel hair growth agents.
Chisato Kubo, Mizuki Ogawa, Norihisa Uehara, Yoshinori Katakura, Yoshinori Katakura   +4 more
doaj   +1 more source

"Properties of Vibrissa follicle cells during follicle development and regeneration, and their interactions with embryonic stem cells." [PDF]

, 2001
Follicular dermal cells possess properties that regulate induction of follicle formation, hair growth, and follicle end bulb regeneration after amputation.
Harris, Susan Jane
core  

Small extracellular vesicles derived from hair follicle neural crest stem cells enhance perineurial cell proliferation and migration via the TGF-β/SMAD/HAS2 pathway

Neural Regeneration Research
Peripheral nerve defect repair is a complex process that involves multiple cell types; perineurial cells play a pivotal role. Hair follicle neural crest stem cells promote perineurial cell proliferation and migration via paracrine signaling; however ...
Yiming Huo, Bing Xiao, Haojie Yu, Yang Xu, Jiachen Zheng, Chao Huang, Ling Wang, Haiyan Lin, Jiajun Xu, Pengfei Yang, Fang Liu   +10 more
doaj   +1 more source

Identifying Quiescent Stem Cells in Hair Follicles [PDF]

, 2017
Hair follicle stem cells (HFSCs) are noted for their relative quiescence and therefore can be distinguished from other cells by their differential history of cell division. Replicating cells can be labeled by pulsing the animals repeatedly with 5-bromo-2'-deoxyuridine (BrdU) or tritiated thymidine ([3H]TdR), thymidine analogs that get incorporated into
Christine N, Rodriguez, Hoang, Nguyen
openaire   +2 more sources

K15 & Id3 expression in intact and regenerating adult vibrissae rodent hair follicles [PDF]

, 2009
The hair follicle can renew itself through an intrinsic stem cell population and has the ability to undergo hair follicle growth cycle; its regenerative activities under normal and experimental conditions together with a feature of easy access make it an
Chen, Bo
core  

Hair follicle germinative epidermal cells: a molecular study [PDF]

, 1999
At the base of the hair follicle epidermal matrix is a population of germinative epidermal (GE) cells that is in close communication with the dermal papilla.
Whitehouse, C.J., Whitehouse, Claire Jenna   +1 more
core  

Augmenting endogenous wnt signaling improves skin wound healing [PDF]

, 2013
Wnt signaling is required for both the development and homeostasis of the skin, yet its contribution to skin wound repair remains controversial. By employing Axin2(LacZ/+) reporter mice we evaluated the spatial and temporal distribution patterns of Wnt ...
Manzano Wilfred R., Fang Mark Y., Girija R Dhamdhere, Anthony E. Oro, Bo Liu, Fang, Mark Y, Whyte, Jemima L., Helms Jill A., Wilfred R. Manzano, Nick D. Evans (474290), Manzano, Wilfred R, Howard Y. Chang (215450), Smith, Andrew A, Manzano, Wilfred R., Whyte, Jemima L, Jemima L. Whyte (474287), Nick D Evans, Helms, Jill A., Andrew A Smith, Anthony E Oro, Andrew A. Smith (474288), Oro Anthony E., Chang, Howard Y., Jemima L Whyte, Liu Bo, Howard Y Chang, Dhamdhere, Girija R, Evans Nick D., Evans, Nick D., Wilfred R. Manzano (474289), Oro, Anthony E., Nick D. Evans¤a, Smith Andrew A., Whyte Jemima L., Liu, Bo, Mark Y. Fang (474292), Wilfred R Manzano, Jill A. Helms (25398), Fang, Mark Y., Smith, Andrew A., Andrew A. Smith, Evans, Nick D, Helms, Jill A, Girija R. Dhamdhere (474291), Girija R. Dhamdhere, Jill A Helms, Mark Y. Fang¤b, Anthony E. Oro (474293), Jill A. Helms, Dhamdhere, Girija R., Mark Y Fang, Chang, Howard Y, Chang Howard Y., Jemima L. Whyte, Oro, Anthony E, Howard Y. Chang, Bo Liu (127343), Dhamdhere Girija R.   +57 more
core   +2 more sources