Cell Transplantation, 2012 Hair follicle stem cells (HFSCs) are potentially useful for the treatment of skin injuries and diseases. To achieve clinical application, a prerequisite must be accomplished: harvesting enough HFSCs from limited skin biopsy.
Shoubing Zhang +9 more
doaj +1 more source
Potential Natural Products Regulation of Molecular Signaling Pathway in Dermal Papilla Stem Cells
Molecules, 2023 Stem cells have demonstrated significant potential for tissue engineering and repair, anti-aging, and rejuvenation. Hair follicle stem cells can be found in the dermal papilla at the base of the follicle and the bulge region, and they have garnered ...
Zar Chi Soe +3 more
doaj +1 more source
The homing of exogenous hair follicle mesenchymal stem cells into hair follicle niches
JCI Insight, 2023 Hair loss is a debilitating condition associated with the depletion of dermal papilla cells (DPCs), which can be replenished by dermal sheath cells (DSCs). Hence, strategies aimed at increasing the populations of DPCs and DSCs hold promise for the treatment of hair loss.
Kaitao Li +13 more
openaire +2 more sources
Establishment of human hair follicle mesenchymal stem cells with overexpressed human hepatocyte growth factor [PDF]
Iranian Journal of Basic Medical Sciences, 2017 Objective(s): Chronic liver disease has become a major health problem that causes serious damage to human health. Since the existing treatment effect was not ideal, we need to seek new treatment methods.
Dan Zhou +3 more
doaj +1 more source
, 2022 S.49-60We compared the growth and differentiation characteristics of hair follicle-derived dermal stem cells with bone marrow mesenchymal stem cells (MSCs). Follicular dermal cells were isolated from whisker hairs of Wistar rats and bone marrow MSCs were
Hoogduijn, M.J. +2 more
core +1 more source
Gab1 and Mapk Signaling Are Essential in the Hair Cycle and Hair Follicle Stem Cell Quiescence
Cell Reports, 2015 Gab1 is a scaffold protein that acts downstream of receptor tyrosine kinases. Here, we produced conditional Gab1 mutant mice (by K14- and Krox20-cre) and show that Gab1 mediates crucial signals in the control of both the hair cycle and the self-renewal ...
Özlem Akilli Öztürk +8 more
doaj +1 more source
Analysis of Sonic Hedgehog signalling pathway gene expression in Basal Cell Carcinoma and in GLII induced systems [PDF]
, 2007 PhDEmbryonic development is regulated by a number of signalling pathways, Which are critical for normal growth. Many of these genes then continue to play an important role in the regulation of cell growth and differentiation in adult.
Ikram, Mohammed S, Ikram, Mohammed. S.
core +4 more sources
Hair follicle epidermal stem cells define a niche for tactile sensation
eLife, 2018 The heterogeneity and compartmentalization of stem cells is a common principle in many epithelia, and is known to function in epithelial maintenance, but its other physiological roles remain elusive.
Chun-Chun Cheng +13 more
doaj +1 more source
Hair Regeneration Methods Using Cells Derived from Human Hair Follicles and Challenges to Overcome
CellsThe hair follicle is a complex of mesenchymal and epithelial cells acquiring different properties and characteristics responsible for fulfilling its inductive and regenerative role.
Ons Ben Hamida +4 more
doaj +1 more source
Extensive Hair-Shaft Elongation by Isolated Mouse Whisker Follicles in Very Long-Term Gelfoam® Histoculture. [PDF]
PLoS ONE, 2015 We have previously studied mouse whisker follicles in Gelfoam® histoculture to determine the role of nestin-expressing plutipotent stem cells, located within the follicle, in the growth of the follicular sensory nerve.
Wenluo Cao +5 more
doaj +1 more source