Results 51 to 60 of about 5,137,800 (295)

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

Behavioral and Historical Processes Jointly Maintain Genetic Connectivity in Fragmented Chinese Water Deer Populations

open access: yesEcology and Evolution
Habitat fragmentation poses a major threat to endangered species by isolating populations and disrupting gene flow. The vulnerable Chinese water deer (Hydropotes inermis) in northeastern China offers a critical case for understanding how fragmented ...
Zongzhi Li   +5 more
doaj   +1 more source

The Extent of Anthropogenic Disturbance on Wetland Area in the Oil Sands Region of Alberta, Canada Between 2000 and 2018

open access: yesLand
Wetlands globally have and continue to undergo modification from anthropogenic and natural environmental factors. To bridge this gap, this study utilised a GIS-based approach to quantify the areal extent of human footprint disturbances to wetlands over ...
Joshua Montgomery   +3 more
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Community perspectives of flagship species: can conservation motivators mitigate human-wildlife conflict?

open access: yesFrontiers in Ecology and Evolution
Public perception of endangered species is crucial for successful management of community-based conservation and sustainability of national parks. By the method of choice experiment, our study evaluated conservation preferences and willingness to donate
Wanyun Xu   +9 more
doaj   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Understanding the interactions among local communities, protected areas and tourism: case studies of Kruger National Park and Purnululu National Park [PDF]

open access: yes, 2010
New management approaches for protected areas emphasise a 'humans in nature' perspective, with protected areas seen as intrinsically connected with surrounding human populations. Tourism often provides a connection between these communities and protected
Strickland-Munro, Jennifer. K.
core  

Seasonal Diet Composition of Goitered Gazelle (Gazella subgutturosa) in an Arid and Semi-Arid Region of Western China

open access: yesAnimals
Global climate change, habitat fragmentation, and human interference have resulted in a significant, ongoing decline in the population of goitered gazelles. Effective conservation strategies require an understanding of resource requirements of threatened
Nan Zhang   +10 more
doaj   +1 more source

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