Results 51 to 60 of about 1,753,274 (299)
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Privately protected areas increase global protected area coverage and connectivity
Nature Ecology & Evolution, 2022 Privately protected areas (PPAs) are increasing in number and extent. Yet, we know little about their contribution to conservation and how this compares to other forms of protected area (PA). We address this gap by assessing the contribution of 17,561 PPAs to the coverage, complementarity and connectivity of existing PA networks in 15 countries across ...
Rachel Palfrey +2 more
openaire +2 more sources
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
LandWetlands globally have and continue to undergo modification from anthropogenic and natural environmental factors. To bridge this gap, this study utilised a GIS-based approach to quantify the areal extent of human footprint disturbances to wetlands over ...
Joshua Montgomery +3 more
doaj +1 more source
Essential planetary health workers: Positioning rangers within global policy
Conservation Letters, 2023 Our planet is facing increasing challenges: climate change, biodiversity loss, pandemics, poverty, and many other problems closely linked to a deteriorating environment.
Sue Stolton +14 more
doaj +1 more source
Attaining Aichi Target 11: How Well Are Marine Ecosystem Services Covered by Protected Areas? [PDF]
, 2014 The spatial coverage of marine and coastal protected areas worldwide has shown a rapid increase in recent years. Over 32% of the world's coral reefs and over 36% of the world's mangrove forests now fall within protected areas. However, simple measures of
Hannah Thomas +4 more
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Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Frontiers in Ecology and EvolutionPublic perception of endangered species is crucial for successful management of community-based conservation and sustainability of national parks. By the method of choice experiment, our study evaluated conservation preferences and willingness to donate
Wanyun Xu +9 more
doaj +1 more source
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
Public Opinion on Marine Protected Areas [PDF]
, 2016 The following results are based on a survey conducted by WWF-Canada to find out more about Canadians' opinions about marine protected ...
Catharine Tunnacliffe
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