Results 171 to 180 of about 292,259 (261)

β‐Catenin/c‐Myc Axis Modulates Autophagy Response to Different Ammonia Concentrations

Advanced Biology, Volume 9, Issue 3, March 2025.
Ammonia, detoxified by the liver into urea and glutamine, impacts autophagy differently at varying levels. Low ammonia activates autophagy via c‐Myc and β‐catenin, while high levels suppress it. Using Huh7 cells and Spf‐ash mice, c‐Myc's role in cytoprotective autophagy is revealed, offering insights into hyperammonemia and potential therapeutic ...
S. Sergio, B. Spedicato, G. Corallo, A. Inguscio, M. Greco, D. Musarò, D. Vergara, A. F. Muro, G. De Sabbata, L. R. Soria, N. Brunetti Pierri, M. Maffia   +11 more
wiley   +1 more source

Trade-offs between nature and people in Ethiopia's protected areas demonstrate challenges in translating global conservation targets into national realities. [PDF]

Nat Ecol Evol
Jago S, Gizaw G, Genanaw B, Langley J, Lulekal E, White JDM, Rowlands AN, Geda T, Wakjira K, Regassa F, Demissew S, Woldeyes F, Abebe W, Jones JPG, Smith RJ, Borrell JS.   +15 more
europepmc   +1 more source

Air‐Pressure–Actuated Vibroacoustic Metamaterial With Tunable Bandgap: Design, Modeling, and Characterization

Advanced Engineering Materials, EarlyView.
This article presents the design, modeling, and characterization of air‐pressure–actuated programmable vibroacoustic metamaterials (PVAMM). The study focuses on leveraging air pressure to dynamically tune resonance frequencies for effective noise attenuation.
William Kaal, Michael M. Becker, Sarah C. L. Fischer   +2 more
wiley   +1 more source

A predictive approach to integrating connectivity into landscape scale protected areas planning. [PDF]

PLoS One
O'Brien P, Carr N, Bowman J.
europepmc   +1 more source

Facilitating Expedited Drug Approval—the Past, Present, and Future of Clinical Trials for Pediatric Rheumatic Disease

Arthritis Care &Research, EarlyView.
Pamela F. Weiss, Hermine I. Brunner
wiley   +1 more source

A Knowledge‐Based Approach for Understanding and Managing Additive Manufacturing Data

Advanced Engineering Materials, EarlyView.
Additive manufacturing processes generate a large amount of data. Effectively managing, understanding, and retrieving information from this data remains a major challenge. Therefore, we propose an ontology‐based approach to integrate heterogeneous data, enable semantic queries, and support decision‐making.
Mina Abd Nikooie Pour, Prithwish Tarafder, Anton Wiberg, Huanyu Li, Johan Moverare, Patrick Lambrix   +5 more
wiley   +1 more source

Creating Ti–Fe α/β Alloys by Diffusion‐Driven Solid‐State Processing

Advanced Engineering Materials, EarlyView.
This study proposes making alloys containing fast diffusing elements that are difficult to produce by ingot metallurgy, by diffusion‐driven solid‐state HIP processing of elemental powders and low‐temperature homogenisation. Here, novel Fe‐Ti α–β alloys are formed having fine α–β lamellae, a small β prior grain size without significant intermetallics ...
Jiaqi Xu, Xun Zhang, Jack M. Donoghue, Albert D. Smith, Rahul Unnikrishnan, Rhys Thomas, Vahid Nekouie, Jie Luo, Dongchen Hu, Michael Preuss, Philip J. Withers   +10 more
wiley   +1 more source

Extent, characteristics and policy applications of Key Biodiversity Areas. [PDF]

Biol Rev Camb Philos Soc
Butchart SHM, Crowe O, Scott T, Plumptre AJ, Eldred M, McKee E, Waliczky Z, Hasani IA, Azpiroz AB, Baisero D, Barasa F, Beresford AE, Bezeng BS, Boyd C, Brooks TM, Buchanan G, Bunting G, Capellan S, Cox N, Davenport TRB, Davies TE, Togna GD, Elliott W, Foster M, Gilbert J, Handley JM, Juffe-Bignoli D, Jones VR, Kingston N, Kivono J, Lamoreux J, Langhammer PF, Lewis J, Liggitt B, Marnewick D, Matiku P, McCreless E, Neugarten RA, Numa C, O'Brien M, Rao M, Raudsepp-Hearne C, Ray JC, Rijal S, Rodríguez JP, Sapijanskas J, Sechrest W, Sneary M, Snyder A, Spiliopoulou K, Starnes T, Tobar C, Surya G, Tognelli MF, Tordoff AW, Toscano MG, Trisurat Y, Upgren A.   +57 more
europepmc   +1 more source

Phase Field Failure Modeling: Brittle‐Ductile Dual‐Phase Microstructures under Compressive Loading

Advanced Engineering Materials, EarlyView.
The approach by Amor and the approach by Miehe and Zhang for asymmetric damage behavior in the phase field method for fracture are compared regarding their fitness for microcrack‐based failure modeling. The comparison is performed for the case of a dual‐phase microstructure with a brittle and a ductile constituent.
Jakob Huber, Jan Torgersen, Ewald Werner
wiley   +1 more source

Hyperdominant Trees Reveal Savanna Vulnerability Under Climate Change. [PDF]

Glob Chang Biol
Alvarez F, Marimon-Junior BH, Marimon BS, da Cruz WJA, Júnior NGR, Béu RG, da Conceição Bispo P, de Souza Medeiros A, Siqueira GM, Bueno ML, de Gois Aquino F, Guilherme FAG, Pinto JRR, Mews HA, Walter BMT, do Couto de Miranda S, Haidar RF, de Oliveira EL, Brandão RDF, Matricardi EAT, Munhoz CBR, de Souza Lima E, Carniello MA, da Cunha Bustamante MM, Morandi PS, de Oliveira EA, Finger Z, das Neves EC, Elias F, Menor IO, de Almeida Reis SM, Phillips O, Feldpausch TR.   +32 more
europepmc   +1 more source