Results 91 to 100 of about 393 (118)
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Cellular Signalling, 2019
Protectin DX (PDX), which is a novel regulator of 5' adenosine monophosphate-activated protein kinase (AMPK), has recently gained attention for its ability to improve several metabolic diseases. However, the function of PDX in vascular endothelial cells remains unclear.
Hwan-Jin Hwang +9 more
openaire +2 more sources
Protectin DX (PDX), which is a novel regulator of 5' adenosine monophosphate-activated protein kinase (AMPK), has recently gained attention for its ability to improve several metabolic diseases. However, the function of PDX in vascular endothelial cells remains unclear.
Hwan-Jin Hwang +9 more
openaire +2 more sources
Clinical and Experimental Pharmacology and Physiology, 2019
AbstractThe role as well as the molecular mechanisms of protectin DX (PDX) in the prevention of hepatic insulin resistance, a hallmark of type 2 diabetes, remains unknown. Therefore, the present study was designed to explore the direct impact of PDX on insulin resistance and to investigate the expression of fetuin‐A and selenoprotein P (SeP ...
Tae Woo Jung +8 more
openaire +3 more sources
AbstractThe role as well as the molecular mechanisms of protectin DX (PDX) in the prevention of hepatic insulin resistance, a hallmark of type 2 diabetes, remains unknown. Therefore, the present study was designed to explore the direct impact of PDX on insulin resistance and to investigate the expression of fetuin‐A and selenoprotein P (SeP ...
Tae Woo Jung +8 more
openaire +3 more sources
Life Sciences
Protectin DX (PDX), a specialized pro-resolving mediator, is an important pharmaceutical compound with potential antioxidant and inflammation-resolving effects. However, the fundamental mechanism by which PDX's ameliorate chronic inflammatory diseases has not yet been elucidated.
Kyeong-Bae, Jeon +6 more
openaire +2 more sources
Protectin DX (PDX), a specialized pro-resolving mediator, is an important pharmaceutical compound with potential antioxidant and inflammation-resolving effects. However, the fundamental mechanism by which PDX's ameliorate chronic inflammatory diseases has not yet been elucidated.
Kyeong-Bae, Jeon +6 more
openaire +2 more sources
European Journal of Lipid Science and Technology, 2015
Oxidative stress and inflammation in retinal pigment epithelium (RPE) play important roles in the development of age‐related macular degeneration (AMD). Docosahexaenoic acid (22:6, n‐3, DHA) is highly concentrated in RPE and can be converted into the active oxygenate derivative protectin DX (PDX).
Yining Dai +4 more
openaire +1 more source
Oxidative stress and inflammation in retinal pigment epithelium (RPE) play important roles in the development of age‐related macular degeneration (AMD). Docosahexaenoic acid (22:6, n‐3, DHA) is highly concentrated in RPE and can be converted into the active oxygenate derivative protectin DX (PDX).
Yining Dai +4 more
openaire +1 more source
Progress in Neuro-Psychopharmacology and Biological Psychiatry
Protectin DX (PDX), a specialized pro-resolving lipid mediator, presents potential therapeutic applications across various medical conditions due to its anti-inflammatory and antioxidant properties. Since type-1 diabetes mellitus (T1DM) is a disease with an inflammatory and oxidative profile, exploring the use of PDX in addressing T1DM and its ...
Ana Paula Farias, Waltrick +6 more
openaire +2 more sources
Protectin DX (PDX), a specialized pro-resolving lipid mediator, presents potential therapeutic applications across various medical conditions due to its anti-inflammatory and antioxidant properties. Since type-1 diabetes mellitus (T1DM) is a disease with an inflammatory and oxidative profile, exploring the use of PDX in addressing T1DM and its ...
Ana Paula Farias, Waltrick +6 more
openaire +2 more sources
Protectin D1 reduces imiquimod-induced psoriasiform skin inflammation
International Immunopharmacology, 2021Weon Ju Lee, Jinjoo Kang, Jun Young Kim
exaly