Results 81 to 90 of about 1,947,937 (269)

Characterization of an mRNA-Encoded Antibody Against Henipavirus

Current Issues in Molecular Biology
Nipah and Hendra viruses are lethal zoonotic pathogens with no approved vaccines or therapeutics. mRNA produced via in vitro transcription enables endogenous protein expression and cost reduction.
Zixuan Liu, Bingjie Sun, Ting Fang, Xiaofan Zhao, Yi Ren, Zhenwei Song, Sijun He, Jianmin Li, Pengfei Fan, Changming Yu   +9 more
doaj   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

The Relationship of Care and Power in the Context of Feminist Care Ethics

Filozofia
Feminist theories of care ethics point out that vulnerability and dependence are an inherent part of caring relationships, while also noting that these aspects and the sense of inequality that stems from them invariably enable the abuse of power. At the
Adriana Jesenková
doaj   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Avant-propos

Bulletin du Centre de Recherche du Château de Versailles
The protection of the king, his family and his residences goes beyond security missions alone. The arrangements put in place for royal protection played a fundamental role in the construction of curial pomp, monarchical authority and the maintenance of ...
Thomas Fressin
doaj   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

FEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança, Eline L. Jansen, Jorine M. Eeftens   +2 more
wiley   +1 more source

Landscape Character Assessment for Sustainable Rural Development in Border Insular Areas: A Case Study of Ano Mirabello, Crete

Agriculture
This article seeks to demonstrate the value of landscape character assessment in addressing the unique needs of remote areas, located at national insular borders, with lower levels of development and economic activity. The paper assesses and presents the
Aikaterini Gkoltsiou
doaj   +1 more source

ROUNDTABLE SESSION 1 THREATS TO INDIGENOUS CRAYFISH POPULATIONS – STUDIES ON A LANDSCAPE LEVEL

Knowledge and Management of Aquatic Ecosystems, 2004
The present paper summarizes the outcome of a round-table discussion on landscape-level perspectives on threats to indigenous European crayfish populations, which took place during the CRAYNET Conference in Halden, Norway in September 2003.
SCHULZ R., SCHULZ H. K.
doaj   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

FEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell, Thomas Walther, Egbert Hoiczyk   +2 more
wiley   +1 more source

Structural and biochemical analysis of a B12 superbinder

FEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices, Jacob J. Whittaker, Dirk J. Slotboom, Albert Guskov   +3 more
wiley   +1 more source