Protection Against Cold Storage-Induced Renal Tubular Cell Apoptosis. [PDF]
Prolonged cold storage (CS) of donor kidneys is associated with tubular cell apoptosis and caspase-3 activation. We have previously shown that pancaspase inhibition prevents CS-associated tubular apoptosis. Because of the nonspecific nature of pancaspase inhibitors, which block all caspases including proinflammatory caspase-1, the effect of specific ...
Jain S +4 more
europepmc +4 more sources
Nitrite enhances liver graft protection against cold ischemia reperfusion injury through a NOS independent pathway [PDF]
Introduction: Nitrite has been found to protect liver graft from cold preservation injury. However, the cell signaling pathway involved in this protection remains unclear. Here, we attempt to clarify if the NOS pathway by using the NOS inhibitor, L-NAME (
Amani Cherif-Sayadi +6 more
doaj +2 more sources
Development of a cross-protective common cold coronavirus vaccine [PDF]
Common cold coronaviruses, such as OC43 and HKU1, typically cause mild respiratory infections in healthy people. However, they can lead to severe illness in high-risk groups, including immunocompromised individuals and older adults.
Tanushree Dangi +2 more
doaj +2 more sources
Research progress on the role of winter swimming in the pathogenesis of acute myocardial infarction [PDF]
Incidence rate and mortality rate of acute cardiovascular disease(CVD), especially acute myocardial infarction(AMI)are significantly higher in cold environment.
SHI Yang, BI Xiao-lei, SHAO Yi-bing
doaj +1 more source
Protection Against Biological Fouling of TB10 Titanium Alloy by Cold - Sprayed Cu (Ag) Coating [PDF]
For improving the biological fouling resistance of TB10 titanium alloy, copper (Cu) and copper - silver (Cu - Ag) coatings were prepared on its surface by cold spraying. The mass fraction of silver in the powder used for manufacturing Cu - Ag coating was
SU Zhi - wei, ZHOU Yan - wen, GUO Cheng, ZHANG Kai - ce, WU Jun - sheng, XU Shuai, WANG Ding
doaj +1 more source
Leptin Gene Protects Against Cold Stress in Antarctic Toothfish [PDF]
Leptin is a cytokine-like peptide, predominantly biosynthesized in adipose tissue, which plays an important role in regulating food intake, energy balance and reproduction in mammals. However, how it may have been modified to enable life in the chronic cold is unclear.
Ying Wang +11 more
openaire +3 more sources
Antibody responses are critical for protection from developing severe COVID-19 following SARS-CoV-2 infection. Here the authors show that antibody responses against SARS-CoV-2 spike protein correlate with neutralizing capacity and protection, are not ...
Stefania Dispinseri +19 more
doaj +1 more source
Stress adaptation and cross-protection of Lactobacillus plantarum KLDS 1.0628
Various stresses are commonly encountered by probiotics in their ecological niches. Effects of adaptation treatments on the heat tolerance of Lactobacillus plantarum KLDS 1.0628 were evaluated. Cells pre-adapted to heat, cold, oxidative, acid, bile salt,
Jiage Ma +5 more
doaj +1 more source
N-octanoyl dopamine, a non-hemodyanic dopamine derivative, for cell protection during hypothermic organ preservation. [PDF]
BACKGROUND: Although donor dopamine treatment reduces the requirement for post transplantation dialysis in renal transplant recipients, implementation of dopamine in donor management is hampered by its hemodynamic side-effects.
Ralf M Lösel +8 more
doaj +1 more source
The therapeutic potential of trifluoperazine against ethanol and cold water stress-induced gastric lesions in rat [PDF]
Gastric erosion is a multifactorial etiological disorder. The study aimed to evaluate the therapeutic effect of trifluoperazine (TFP ) on gastric lesioninduced by cold-water stress and ethanol in rats.
Mohammad Khoshnoud +5 more
doaj +1 more source

