Results 31 to 40 of about 15,853,139 (285)
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Le fonds Pascal du ministère de la Culture et de la Communication soutien à l'interprétation doit permettre aux chercheurs de communiquer en langue française le résultat de leurs travaux EA ECOLDUR CT ?National audienceFew scientific and technical ...
Cordeau, Stephane, Piva, G., Poyac, C.
core +3 more sources
Situation des problèmes phytosanitaires du myrtillier (Vaccinium corymbosum) au Maroc
La présente étude porte sur les problèmes phytosanitaires du myrtillier au Maroc. Il s’agit de la première en son genre et vise à diagnostiquer les problèmes phytosanitaires du myrtillier et les pratiques des agriculteurs par le biais d’enquêtes auprès ...
Sara NOUERE, Said AMIRI, Rachid LAHLALI
doaj
Citrullus lanatus, a new host of Bipolaris spicifera in Morocco
Bipolaris spicifera was isolated from necrotic leaves of field-grown watermelon plants from the Taroudant area of southern Morocco. The pathogenicity of this fungus was tested on the leaves of two cultivars of watermelon (Peacock 124 and Mabrouka) widely
M. El Mhadri +3 more
doaj +1 more source
Les problématiques posées par les intrants sous leurs diverses formes ont récemment bénéficié d’une plus large prise en compte, et d’un gain d’intérêt auprès du grand public et des autorités compétentes.
Davillerd Yann, Marchand Patrice A.
doaj +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Principales maladies et ravageurs affectant la culture de myrtillier
La production du myrtillier a représenté 12,53% de la production des petits fruits rouges au Maroc durant la campagne agricole 2017-2018. Cependant, le myrtillier est attaqué par plusieurs ennemis qui pourraient entraîner des pertes économiques ...
Sara NOUERE, Said AMIRI, Rachid LAHLALI
doaj
Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim +7 more
wiley +1 more source
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose +9 more
wiley +1 more source

