Results 91 to 100 of about 13,620,416 (309)

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

Two-level home IoT network protection system

open access: yesТехнічна інженерія
The article discusses the problems of protecting home IoT networks, in particular, ways to ensure security during data transmission in systems built on the basis of ESP32 microcontrollers.
O.O. Shelukha   +2 more
doaj   +1 more source

The protection of minority languages at the european level

open access: yesRevista de Derecho Político, 2013
The linguistic diversity within the European Union is an expression of the multiculturalism and plurality which is the basis of today’s Europe. That is why the EU institutions have adopted various regulations aimed at the promotion, preservation and ...
María Acracia Núñez Martínez
doaj   +1 more source

L‐aspartate oxidase provides new insights into fumarate reduction in anaerobic darkness in Synechocystis sp. PCC6803

open access: yesFEBS Letters, EarlyView.
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil   +3 more
wiley   +1 more source

Data protection at the cost of economic growth? ECRI Commentary No. 11, 16 November 2012 [PDF]

open access: yes, 2012
The Data Protection Regulation proposed by the European Commission contains important elements to facilitate and secure personal data flows within the Single Market.
Pyykko, Elina
core  

RNA‐related functions of BRCA2 in transcription, replication, and genome stability

open access: yesFEBS Letters, EarlyView.
Beyond its role in homologous recombination, BRCA2 regulates R‐loop homeostasis, DNA–RNA hybrid resolution, RNA polymerase II dynamics, and transcriptional activation. Disruption of any of these functions can contribute to genome instability, inflammatory signaling, and tumorigenesis. BRCA2 is a central tumor suppressor protein best known for its roles
Lucia Alvaro‐Aranda   +2 more
wiley   +1 more source

Progress on Effect of Clay Mineral-Biocomposite Colloids on Radionuclides Migration and Mechanism

open access: yesHe huaxue yu fangshe huaxue
A comprehensive understanding and scientific assessment of radionuclides migration are of great significance for nuclear environmental safety assessment and for the design of effective removal and remediation strategies for radioactive contaminated sites.
Qing-feng TANG   +6 more
doaj   +1 more source

The ubiquitin system in normal and infected germinal center B cells

open access: yesFEBS Letters, EarlyView.
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis   +2 more
wiley   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

open access: yesFEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward   +2 more
wiley   +1 more source

Byte-level Object Bounds Protection

open access: yesCoRR
Low-level C programs remain highly vulnerable to out-of-bounds memory corruption. State-of-the-art precise defenses either introduce severe runtime overhead due to metadata memory lookups, or break standard C semantics by disallowing partial structs or the creation of an object's end address (EA), a legal operation ubiquitous in real-world C code ...
openaire   +3 more sources

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