Results 131 to 140 of about 2,508,909 (311)
Molecular Oncology, EarlyView.We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto +8 more
wiley +1 more source
Assessment of Health Professionals' Attitudes on Radiation Protection Measures. [PDF]
Int J Environ Res Public Health, 2021 Goula A +5 more
europepmc +1 more source
HOW DO FIRING COSTS AFFECT INNOVATION AND GROWTH WHEN WORKERS’ ABILITY IS UNKNOWN – EMPLOYMENT PROTECTION AS A BURDEN ON A FIRM’S SCREENING PROCESS [PDF]
This paper analyzes the implication of employment protection legislation on a firm's screening process. We present a model in which human-capital-intensive firms (hightech) with imperfect information about their workers' type attempt during a trial ...
Binyamin Berdugo, Sharon Hadad
core
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Corporate Governance in the Asian Financial Crisis [PDF]
The "Asian Crisis" of 1997-98 affected all the "emerging markets" open to capital flows. Measures of corporate governance, particularly the effectiveness of protection for minority shareholders, explain the extent of depreciation and stock market decline
Alasdair Breach +3 more
core
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Oñati Socio-Legal Series, 2015 In this article I make a reflection about the art. 1 L0 1/2004 of 28 December of integral Protection Measures against Gender Violence (law 1/2004) and its relations with sexual trafficking victims, who are absent in these regulation, and as a result any ...
Izaskun Orbegozo
doaj
Assessment of COVID-19 prevention and protection measures in hospitals. [PDF]
Clean Eng Technol, 2022 Thomas A, Suresh M.
europepmc +1 more source
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source