Results 121 to 130 of about 4,404,286 (307)

Tumor‐stromal crosstalk and macrophage enrichment are associated with chemotherapy response in bladder cancer

open access: yesFEBS Open Bio, EarlyView.
Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold   +11 more
wiley   +1 more source

Perfection of Methods and Means of Tests Physical Protection Equipment

open access: yesБезопасность информационных технологий, 2011
In the work questions of perfection of methods and means of researches of significant parameters of means of physical protection equipment (PPE), important state objects used for protection are considered.
I. A. Kozhevnikov
doaj  

Digital Rights Management, Intellectual Property Rights Protection and Economic development: The case of digital piracy in the South Mediterranean countries [PDF]

open access: yes
: The potential benefits that could be gained from information technologies in South Mediterranean economies are constrained by both DRM and institutional protection related to Intellectual Property Rights.
Alaoui Belghiti, Moulay Abdelaziz   +2 more
core   +1 more source

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

open access: yesFEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand   +2 more
wiley   +1 more source

UK’s Implementation of the Anti-Circumvention Provisions of the EU Copyright Directive: An Analysis [PDF]

open access: yes, 2004
The debate surrounding utilization of technological protection measures to secure copyrighted works in the digital arena has raised many an eyebrow in the past few years.
Shah, Aashit
core   +1 more source

Alcohol‐induced altered glycans in human tracheal epithelial cells promote bacterial adhesion

open access: yesFEBS Open Bio, EarlyView.
Alcohol induces altered glycans to promote bacteria adhesion. Heavy alcohol drinking is known to increase the risk of bacterial pneumonia. However, the link between alcohol levels and risk of infection remains underexplored. Recently, we found that alcohol induced α2‐6sialo mucin O‐glycans in human tracheobronchial epithelial cells, which mediated the ...
Pi‐Wan Cheng   +2 more
wiley   +1 more source

Development of human monoclonal antibodies against TARM1 by yeast display

open access: yesFEBS Open Bio, EarlyView.
Human monoclonal antibodies against TARM1 are generated by yeast display‐guided selection. These antibodies bind to soluble and cell‐surface forms of TARM1. Also, these antibodies exhibit agonistic activity in the NFAT‐GFP reporter assay, indicating that TARM1 signaling can be functionally modulated by antibodies and suggesting TARM1 as a potential ...
Rikio Yabe   +5 more
wiley   +1 more source

Sustainable Antifungal Potential of the Essential Oil of Litsea cubeba: Multifaceted Mechanisms Targeting Fusarium verticillioides

open access: yesJournal of Chemistry
The essential oil of Litsea cubeba, extracted from its fruits, demonstrates significant antifungal activity against Fusarium verticillioides, with an EC50 value of 0.122 μL/mL, comparable to the synthetic fungicide methyl thiophanate (EC50: 0.108 μL/mL).
Kai-Wen Wu   +6 more
doaj   +1 more source

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

open access: yesFEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

Croatian Accession to the European Union: Institutional Challenges [PDF]

open access: yes
Awareness of the need for environmental protection must in Croatia be translated into a clear, overall and long-term concept, particularly because of the process of rapprochement with the European Union (EU), in which it is one of the key topics.
Alida Ban, Katarina Ott
core  

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