Results 101 to 110 of about 4,404,286 (307)

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

SUBSTANTIATION OF THE NEED TO IMPLEMENT A CONTINUOUS INFORMATION SECURITY PROCESS AT ENTERPRISES

Наука Красноярья
The article discusses information security in the system of an industrial enterprise. Attention is focused on the need to implement a continuous information security process to protect all information assets from leaks, theft and unauthorized disclosure,
Elena N. Syshchikova, Ekaterina E. Makarova, Marina N. Muratova   +2 more
doaj   +1 more source

Job protection renders minimum wages less harmful [PDF]

Individual labour productivities are often unobservable for firms when hiring new workers. Job protection may prevent firms ex post from using information about labour productivities.
Schöb, Ronnie, Thum, Marcel
core  

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Perspective Systems and Methods of Protection of Confidential Talks in the Car

Безопасность информационных технологий, 2014
The article analyzes the known systems and methods of protection of confidential talks in the car, on the basis of this analysis revealed their major shortcomings and proposed new promising systems, in which either there are not the drawbacks, or their ...
Vyacheslav Igorevich Lobastov, Aleksandr Alekseevich Tarasov, Dmitriy Borisovich Halyapin   +2 more
doaj  

ИНФОРМАЦИСКА БЕЗБЕДНОСТ ВО САД [PDF]

Bezbednosni Dijalozi, 2010
In the modern world, the IT security has grown into a part of the general concept of national security. The article argues that the parameters of the theory of information warfare arise from the fundamental postulates of the general theory of security ...
Ванчо КЕНКОВ
doaj  

CRYPTOGRAPHIC PROTECTION OF INFORMATION

Vestnik obrazovatel'nogo konsortsiuma Srednerusskii universitet. Informatsionnye tekhnologii, 2021
Tatiana Yurievna Haikhan, Valery Vladimirovich Nikulin   +1 more
openaire   +1 more source

The Lautenberg Act: Chemical Safety Overhaul of the Toxic Substances Control Act [PDF]

, 2016
On June 22, 2016, President Obama signed the Frank Lautenberg Chemical Safety for the 21st Century Act (Lautenberg Act), a landmark bipartisan compromise legislation designed to overhaul the Toxic Substances Control Act (TSCA).
Rosen, Alyssa S.
core   +1 more source

Revisiting Mission‐Oriented Cancer Research to tackle the increasing burden of cancer in Europe–a policy perspective

Molecular Oncology, EarlyView.
Translational cancer research and its implementation through competitively selected Comprehensive Cancer Centers across Europe should be the primary policy focus for addressing the increasing cancer burden in Europe and counteract the present main strategy to convert cancer to a chronic disease.
Manuel Heitor, Julio Celis, Ulrik Ringborg   +2 more
wiley   +1 more source