Results 91 to 100 of about 1,245,468 (316)

Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

open access: yesMolecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski   +12 more
wiley   +1 more source

Perspective Systems and Methods of Protection of Confidential Talks in the Car

open access: yesБезопасность информационных технологий, 2014
The article analyzes the known systems and methods of protection of confidential talks in the car, on the basis of this analysis revealed their major shortcomings and proposed new promising systems, in which either there are not the drawbacks, or their ...
Vyacheslav Igorevich Lobastov   +2 more
doaj  

ИНФОРМАЦИСКА БЕЗБЕДНОСТ ВО САД [PDF]

open access: yesBezbednosni Dijalozi, 2010
In the modern world, the IT security has grown into a part of the general concept of national security. The article argues that the parameters of the theory of information warfare arise from the fundamental postulates of the general theory of security ...
Ванчо КЕНКОВ
doaj  

A Study of the Geo-Herbalism of Evodiae Fructus Based on a Flow-Injection Mass Spectrometric Fingerprinting Method Combined with Chemometrics

open access: yesMolecules, 2015
A flow-injection mass spectrometric (FIMS) fingerprinting method in combination with principal component analysis (PCA) was used to study the geo-herbalism of Evodiae Fructus (EF) samples.
Yang Zhao   +4 more
doaj   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola   +11 more
wiley   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

open access: yesMolecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller   +10 more
wiley   +1 more source

Amended Act on the Protection of Personal Information (2020) [PDF]

open access: yes, 2022
Personal Information Protection Commission
core  

Development of human monoclonal antibodies against TARM1 by yeast display

open access: yesFEBS Open Bio, EarlyView.
Human monoclonal antibodies against TARM1 are generated by yeast display‐guided selection. These antibodies bind to soluble and cell‐surface forms of TARM1. Also, these antibodies exhibit agonistic activity in the NFAT‐GFP reporter assay, indicating that TARM1 signaling can be functionally modulated by antibodies and suggesting TARM1 as a potential ...
Rikio Yabe   +5 more
wiley   +1 more source

Institute of Child Protection Studies Research Update

open access: yes, 2015
ICPS aims to enhance the well-being of children, young people and families through quality research, evaluation, training and community education. The Research Update aims to keep stakeholders informed about the projects we are undertaking. The December
Institute of Child Protection Studies
core  

Digital Soil Information System for Ireland – Scoping Study [PDF]

open access: yes, 2007
This synthesis report has been prepared as part of the Environmental Research Technological Development and Innovation (ERTDI) Programme under the Productive Sector Operational Programme 2000-2006. This programme is financed by the Irish Government under
Fealy, Reamonn, Daly, Karen M.
core  

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