Results 71 to 80 of about 1,061,603 (267)

Phosphoinositides and inositol phosphates as molecular glues

open access: yesFEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry   +9 more
wiley   +1 more source

SUBSTANTIATION OF THE NEED TO IMPLEMENT A CONTINUOUS INFORMATION SECURITY PROCESS AT ENTERPRISES

open access: yesНаука Красноярья
The article discusses information security in the system of an industrial enterprise. Attention is focused on the need to implement a continuous information security process to protect all information assets from leaks, theft and unauthorized disclosure,
Elena N. Syshchikova   +2 more
doaj   +1 more source

Data protection and freedom of information [PDF]

open access: yesBMJ, 2005
The law is only a catalyst for changing the culture in the NHS T he protection and use of confidential information about patients has had welcome priority in the government's thinking in recent years1–3 and becomes more important with the planned introduction of the new NHS care records service.4 The legal framework for the processing and use of ...
openaire   +2 more sources

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Perspective Systems and Methods of Protection of Confidential Talks in the Car

open access: yesБезопасность информационных технологий, 2014
The article analyzes the known systems and methods of protection of confidential talks in the car, on the basis of this analysis revealed their major shortcomings and proposed new promising systems, in which either there are not the drawbacks, or their ...
Vyacheslav Igorevich Lobastov   +2 more
doaj  

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

ИНФОРМАЦИСКА БЕЗБЕДНОСТ ВО САД [PDF]

open access: yesBezbednosni Dijalozi, 2010
In the modern world, the IT security has grown into a part of the general concept of national security. The article argues that the parameters of the theory of information warfare arise from the fundamental postulates of the general theory of security ...
Ванчо КЕНКОВ
doaj  

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

Ca(OH)2-modified Camellia oleifera shell biochar: preparation, characterization, and adsorption of NH4+ and PO43−

open access: yesBiochar X
Excessive nitrogen and phosphorus in aquatic systems trigger eutrophication and environmental contamination. Herein, Ca(OH)2-modified Camellia oleifera shell biochar was fabricated as an adsorbent for NH4+ and PO43− removal, with the effects of contact ...
Min Chen   +6 more
doaj   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

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