Results 51 to 60 of about 1,245,468 (316)

PARK(ing) time–How park deficiency affects the biological clock in a Drosophila model of Parkinson's disease

open access: yesFEBS Letters, EarlyView.
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara   +3 more
wiley   +1 more source

Effective Documents Analysis Tools for Information Security

open access: yesБезопасность информационных технологий, 2012
The new method of psychological characteristic estimating and application which is based on this method is under consideration. Abovementioned application is a part of an automated information security complex (AISC).
S. D. Kulik, N. E. Gunko
doaj  

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Classification of information Resources Using Open Criteria within Current Legislative Documents of Republic of Belarus

open access: yesНаука и техника, 2004
The paper contains analysis of classification aspects that describe information resources using open criteria. The paper substantiates the necessity to carry out an analysis of information resource content on the basis of the given criteria while ...
J. M. Krotjuk   +2 more
doaj   +1 more source

Animal protection and information avoidance

open access: yes, 2023
Social scientists are increasingly interested in information avoidance (IA)—the active decision to refrain from information. However, processing information on animal protection in German livestock systems has not been systematically studied before. We close this gap by conducting a web-based survey in Germany with a focus on abdicating responsibility ...
Richard Völker, Sven Gruener
openaire   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

Online Personal Data Processing and EU Data Protection Reform. CEPS Task Force Report, April 2013 [PDF]

open access: yes, 2013
This report sheds light on the fundamental questions and underlying tensions between current policy objectives, compliance strategies and global trends in online personal data processing, assessing the existing and future framework in terms of effective ...
Luchetta, Giacomo, Irion, Kristina
core  

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

Estimation of radio pulse parameters with linear frequency modulation

open access: yesРадіоелектронні і комп'ютерні системи
The subject of this article is the process of estimating the parameters of a pulse signal with linear frequency modulation (LFM) used in airborne radar systems, particularly in synthetic aperture radars (SAR).
Volodymyr Pavlikov   +3 more
doaj   +1 more source

The Department of Environmental Protection's Information Resource Center: A full-service, scientific, technical and policy library

open access: yes, 1994
This pamphlet describes the services offered by the DEP's Information Resource Center (IRC). The pamphlet tells who is eligible for which services and also describes the IRC's collection.

core   +1 more source

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