Results 31 to 40 of about 1,014,505 (247)
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Function‐driven design of a surrogate interleukin‐2 receptor ligand
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Biometric Feature Script for Information Security
Special studies related to the development of rules for making decisions on the psychological characteristics of the offender in his manuscript handwriting with the goal of ensuring information security.
N. E. Gunko
doaj
Time after time – circadian clocks through the lens of oscillator theory
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
Structural biology of ferritin nanocages
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Use of Signs of Handwriting for Information Security Systems
Special studies related to the development of rules for making decisions ion on the psychological characteristics of the offender in his manuscript handwriting with the goal of ensuring information security are made.
N. E. Gunko
doaj
Genetic testing: ethical aspects
The aim of this article is to provide an analysis of the main issues related to the application of predictive medicine by analysing the most significant ethical implications.
Bin Paola +7 more
doaj +1 more source
The Modern-Era Retrospective analysis for Research and Applications, Version 2 (MERRA-2) is widely used as an advanced model dataset for the understanding of global climate change.
Yang Ou +10 more
doaj +1 more source
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
MATHEMATICS ALGORITHMS OF THE INFORMATION PROTECTION
There were discussed mathematics algorithms of the information protection with purpose to use the main methods of the cryptography algorithm in the medicine.
I. M. Shupiatskyi
doaj +1 more source

