Results 111 to 120 of about 531,678 (162)
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Molecular cloning of a protective antigen of schistosomes
Nature, 1987The complementary DNA sequence encoding the Mr 28,000 antigen of Schistosoma mansoni has been isolated and expressed in Escherichia coli. Experimental vaccination of rats, hamsters and monkeys with a recombinant fusion protein induces a strongly cytotoxic antibody response.
J M, Balloul +8 more
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Characterization of protective antigens and the protective immune response
Veterinary Microbiology, 1993The protective immune response to a vaccine may be due to the presence of circulating antibody (humoral immunity), the actions of sensitized T-lymphocytes (cell-mediated immunity), the presence of secretory IgA on mucosal surfaces (mucosal immunity), or a combination of these factors. In general, humoral immunity is felt to be particularly important in
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Localization of protective antigens in Trighostrongylus colubriformis
International Journal for Parasitology, 1991In order to localize protective antigens in Trichostrongylus colubriformis, adult worms were microdissected and the capacity of worm tissues to protect guinea pigs against infection examined. The results suggest that T. colubriformis protective antigens are widely distributed in the body and are not concentrated in the intestine or glandular structures.
T L, Rothwell, N C, Sangster
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Specificity of Trichostrongylus colubriformis Protective Antigens
The Journal of Parasitology, 1981FIGURE 1. Circulating antigens in the serum of a cynomolgus macaque infected with tetrathyridia in M. corti. Center well (c) contains RAS/E; wells 1 to 3 contain serum from host number 1 (splenectomized) at days 91, 98, 105 p.i.; wells 4 to 6 contain serum from host number 2 (intact) for the same time periods.
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Hsp70 in parasites: as an inducible protective protein and as an antigen
Experientia, 1994The heat shock (HS) response is a general homeostatic mechanism that protects cells and the entire organism from the deleterious effects of environmental stresses. It has been demonstrated that heat shock proteins (HSP) play major roles in many cellular processes, and have a unique role in several areas of cell biology, from chronic degenerative ...
MARESCA, Bruno, G. S. Kobayashi
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[Search for protective antigens of hookworms].
Wiadomosci parazytologiczne, 2006Hookworms are very important blood sucking nematode parasites of humans and domestic animals. The host with a heavy infection can lose almost a cup of blood per day. This may contribute to anemia which is associated with many physical and mental developmental insults.
Marcin Wiśniewski +3 more
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A HEAT STABLE PROTECTIVE STAPHYLOCOCCAL ANTIGEN
Australian Journal of Experimental Biology and Medical Science, 1960SUMMARYA strain of staphylococci, chosen for the very marked enhancement by mucin of its intraperitoneal virulence to mice, was cultured in sloppy agar.The supernatant fluids obtained were of low toxicity and were highly potent as active immunizing agents in mice against lethal intraperitoneal challenge by the homologous strain in mucin suspension. The
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Hymenolepis diminuta: The origin of protective antigens
Experimental Parasitology, 1982Abstract Mice were infected orally with 1,6, or 30 cysticercoids of Hymenolepis diminuta . These were allowed to develop for different periods of time before elimination with anthelminthic, thus exposing the hosts to antigens from the prestrobilate, early strobilate, or fully strobilate worms.
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A Soluble Protective Antigen of Trypanosoma brucei
Nature, 1960Trypanosoma brucei in quantities sufficient for antigenic analysis was obtained by harvesting the blood of rats on the third day of infection by the protozoon, when the fulminating parasitaemia is at its height. The trypanosomes were separated from the blood by centrifugation and the resulting mash was preserved by freeze drying.
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Finding Protective Bacterial Antigens
2012Current vaccine development efforts are mainly focused on opportunistic pathogens that are frequent colonizers and have complex pathogenesis and interaction with the human host. Therefore, more sophisticated and comprehensive vaccine development approaches have to be considered than for strictly pathogenic bacteria with well-defined virulence ...
Guido Grandi, Eszter Nagy
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