Results 111 to 120 of about 527,152 (301)

Protective antigen domain 4 of Bacillus anthracis as a candidate for use as vaccine for anthrax

, 2019
Existing research for using the protective antigen (PA) of Bacillus anthracis as a vaccine component shows that protection against anthrax may be obtained using fragments of this protein.
Niemcewicz, M., Naylor, K., Glowacka, P., Graniak, G., Żakowska, D., Rutyna, P.   +5 more
core   +1 more source

Parasite Antigens in Protection, Diagnosis and Escape: Plasmodium

, 1985
In the hundred years since Laveran first described the malaria parasite as the cause of intermittent fevers, the basic biological questions posed at the end of his paper have been answered. The pathology of acute or chronic malaria infection is however still far from being fully understood and despite the accumulated knowledge of a century, the disease
openaire   +3 more sources

Immunoinflammatory Mechanisms and Biocompatibility of Bioactive Dental Biomaterials: From Fundamental Insights to Clinical Translation

Advanced Healthcare Materials, EarlyView.
Surface‐host dialogue at the implant interface governs biological fate and osseointegration. Surface physicochemical properties of titanium (Ti) dental implants, including microgrooves, nanopatterns, nanotopography, roughness, and wettability, modulate the initial adsorption of proteins and the formation of a dynamic biointerface.
Daniela Moreira Cunha, Amanda Paino Santana, Marta Maria Alves Pereira, Mariana Martins Guerreiro, Jose Mauro Granjeiro, Jamil Awad Shibli, Jeroen J. J. P. van den Beucken, Anton Sculean, Rafael Scaf de Molon, Erica Dorigatti de Avila   +9 more
wiley   +1 more source

Anthrax Vaccines in the 21st Century

Vaccines
Vaccination against Bacillus anthracis is the best preventive measure against the development of deadly anthrax disease in the event of exposure to anthrax either as a bioweapon or in its naturally occurring form.
Apostolos P. Georgopoulos, Lisa M. James
doaj   +1 more source

Immunologic Response of Unvaccinated Workers Exposed to Anthrax, Belgium

Emerging Infectious Diseases, 2009
To determine immunologic reactivity to Bacillus anthrax antigens, we conducted serologic testing of workers in a factory that performed scouring of wool and goat hair.
Pierre Wattiau, Marc Govaerts, Dimitrios Frangoulidis, David Fretin, Esther Kissling, Mieke Van Hessche, Bernard China, Martine Poncin, Yvo Pirenne, Germaine Hanquet   +9 more
doaj   +1 more source

Natural Biomaterials for Osteochondral Repair: From Source to Strategy

Advanced Healthcare Materials, EarlyView.
Biological origin‐guided overview of natural biomaterials and therapeutic strategies for osteochondral tissue engineering. The circular diagram categorizes representative materials and strategies into plant/algae‐derived, microbial‐derived, animal‐derived, and human‐derived sources, centered on an osteochondral defect repair model.
Hengyu Liu, Hanyang Zhang, Wenbo Yang, Hao Chen, Jincheng Wang, Fei Chang   +5 more
wiley   +1 more source

Structural and stability studies on domain IV of anthrax toxin protective antigen (PA); its role in anthrax pathogenesis

, 2018
Thesis (Ph.D.)-- Wichita State University, College of Liberal Arts and Sciences, Dept. of Chemistry1:Introduction -- 2: Long-range stabilization of anthrax protective antigen upon binding to CMG2 -- 3: Stability of domain IV of the anthrax toxin ...
Mamillapalli, Sireesha
core  

Production and purification of Bacillus anthracis protective antigen

, 2012
Protective antigen (PA) plays crucial roles in the pathogenicity and virulence of Bacillus anthracis. Animals or human immunised with the protein acquire a complete protection against the disease.
Natalia, Lily, Tarigan, Simson, Adji, Rahmat S   +2 more
core   +2 more sources

Questionable Efficacy of Therapeutic Antibodies in the Treatment of Anthrax

mSphere, 2019
Inhalational anthrax caused by Bacillus anthracis, a spore-forming Gram-positive bacterium, is a highly lethal infection. Antibodies targeting the protective antigen (PA) binding component of the toxins have recently been authorized as an adjunct to ...
Jean-Nicolas Tournier, Clémence Rougeaux, Fabrice V. Biot, Pierre L. Goossens   +3 more
doaj   +1 more source

Affinity‐Tuned Albumin Hitchhiking Extends the Bioorthogonal Capture Window in Pretargeting Radiotheranostics

Advanced Healthcare Materials, EarlyView.
Pharmacokinetic engineering of clickable radioligands was achieved via albumin hitchhiking approach within a pretargeted radiotheranostics delivery platform. This approach reduced rapid renal elimination, expanded bioorthogonal capture window, boosted tumor uptake by ∼3.5‐fold, and improved the tumor‐to‐liver ratio by ∼6‐fold.
Xie He, Nicholas L. Fletcher, Gayathri R. Ediriweera, Yifei Zhu, James Humphries, Christopher B. Howard, Jiazheng Wang, Craig A. Bell, Kristian Kempe, Kristofer J. Thurecht   +9 more
wiley   +1 more source