Results 301 to 310 of about 697,104 (329)
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Specificity of Trichostrongylus colubriformis Protective Antigens
The Journal of Parasitology, 1981FIGURE 1. Circulating antigens in the serum of a cynomolgus macaque infected with tetrathyridia in M. corti. Center well (c) contains RAS/E; wells 1 to 3 contain serum from host number 1 (splenectomized) at days 91, 98, 105 p.i.; wells 4 to 6 contain serum from host number 2 (intact) for the same time periods.
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Acid induced unfolding of anthrax protective antigen
Biochemical and Biophysical Research Communications, 2003Acidic pH plays an important role in the membrane insertion of protective antigen (PA) of anthrax toxin leading to the translocation of the catalytic moieties. The structural transitions occurring in PA as a consequence of change in pH were investigated by fluorescence and circular dichroism measurements.
Pradeep K, Gupta +6 more
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A HEAT STABLE PROTECTIVE STAPHYLOCOCCAL ANTIGEN
Australian Journal of Experimental Biology and Medical Science, 1960SUMMARYA strain of staphylococci, chosen for the very marked enhancement by mucin of its intraperitoneal virulence to mice, was cultured in sloppy agar.The supernatant fluids obtained were of low toxicity and were highly potent as active immunizing agents in mice against lethal intraperitoneal challenge by the homologous strain in mucin suspension. The
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Nematode antigens in protection, diagnosis and pathology
Veterinary Immunology and Immunopathology, 1987A thorough study of parasite antigens is a prerequisite for control programmes based on protection by vaccination, accurate serodiagnosis and perhaps immune modulation to diminish pathological sequelae. Stage specific surface secreted and somatic antigens may be of particular value in proceeding towards these goals.
R M, Parkhouse +3 more
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Anthrax Protective Antigen: Prepore-to-Pore Conversion
Biochemistry, 1999PA(63), the active 63 kDa form of anthrax protective antigen, forms a heptameric ring-shaped oligomer that is believed to represent a precursor of the membrane pore formed by this protein. When maintained at pH >/=8.0, this "prepore" dissociated to monomeric subunits upon treatment with SDS at room temperature, but treatment at pH
C J, Miller, J L, Elliott, R J, Collier
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Characterization of protective antigens and the protective immune response
Veterinary Microbiology, 1993The protective immune response to a vaccine may be due to the presence of circulating antibody (humoral immunity), the actions of sensitized T-lymphocytes (cell-mediated immunity), the presence of secretory IgA on mucosal surfaces (mucosal immunity), or a combination of these factors. In general, humoral immunity is felt to be particularly important in
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Localization of protective antigens in Trighostrongylus colubriformis
International Journal for Parasitology, 1991In order to localize protective antigens in Trichostrongylus colubriformis, adult worms were microdissected and the capacity of worm tissues to protect guinea pigs against infection examined. The results suggest that T. colubriformis protective antigens are widely distributed in the body and are not concentrated in the intestine or glandular structures.
T L, Rothwell, N C, Sangster
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Plasmodium berghei: Selective release of “protective” antigens
Experimental Parasitology, 1977Abstract BALB c mice infected with Plasmodium berghei produced high levels of immunoglobulins after the first peak parasitemia at which time the malaria parasites were mainly present in reticulocytes and not in oxyphilic red blood cells. Attempts at active immunization with intact parasitized reticulocytes were successful, while immunization ...
L G, Poels +3 more
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Protective Antigens of Vibrio Cholerae
1989The disease cholera in the epidemic form is mainly caused by the gram- negative bacterium Vibrio cholerae, belonging to the 01 serovar. The or-ganism also exists in two serotypes (Inaba and Ogawa) and biotypes (clas-sical and El Tor). It is known that the diarrheagenic syndrome in cholera patients is primarily caused by an enterotoxin (cholera toxin ...
Asoke C. Ghose, Chiranjib Dasgupta
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Genetic identification of antigens protective against coccidia
Parasite Immunology, 2006SUMMARY The Eimeria species, causative agents of the disease coccidiosis, are genetically complex protozoan parasites endemic in livestock. Drug resistance remains commonplace among the Eimeria, and alternatives to chemotherapeutic control are being sought. Vaccines based upon live formulations of parasites are effective, but production costs are high,
D P, Blake, M W, Shirley, A L, Smith
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