Results 311 to 320 of about 697,104 (329)

Unfolding transitions of Bacillus anthracis protective antigen

Archives of Biochemistry and Biophysics, 2007
Protective antigen (PA) is an 83kDa protein which, although essential for toxicity of Bacillus anthracis, is harmless and an effective vaccine component. In vivo it undergoes receptor binding, proteolysis, heptamerisation and membrane insertion. Here we probe the response of PA to denaturants, temperature and pH.
Chalton DA, Kelly IF, McGregor A, Ridley H, Watkinson A, Miller J, Lakey JH   +6 more
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Antigen protection of monoclonal antibodies undergoing labelling

Journal of Immunological Methods, 1990
The effectiveness of a methodology designed to protect the antigen binding capacity of monoclonal antibodies undergoing labelling with a number of reagents was examined. The antigen binding sites of monoclonal antibodies were protected by complexing them with their antigen.
M, Ramjeesingh, M, Zywulko, A, Rothstein, R, Whyte, E Y, Shami   +4 more
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Protective antigen and extractable antigen 1 based chimeric protein confers protection against Bacillus anthracis in mouse model

Molecular Immunology, 2014
Recombinant bivalent chimeric protein was generated comprising of domain 4 of protective antigen (PA4) and carboxy terminal region of extractable antigen 1 (EA1C) by overlap extension PCR. The immunogenicity and protective efficacy of recombinant chimeric protein (PE) and protein mixture (PAEA) along with the individual components, PA4 and EA1C were ...
Shivakiran S, Makam, Joseph J, Kingston, Murali S, Harischandra, Harsh V, Batra   +3 more
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A Soluble Protective Antigen of Trypanosoma brucei

Nature, 1960
Trypanosoma brucei in quantities sufficient for antigenic analysis was obtained by harvesting the blood of rats on the third day of infection by the protozoon, when the fulminating parasitaemia is at its height. The trypanosomes were separated from the blood by centrifugation and the resulting mash was preserved by freeze drying.
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Hymenolepis diminuta: The origin of protective antigens

Experimental Parasitology, 1982
Abstract Mice were infected orally with 1,6, or 30 cysticercoids of Hymenolepis diminuta . These were allowed to develop for different periods of time before elimination with anthelminthic, thus exposing the hosts to antigens from the prestrobilate, early strobilate, or fully strobilate worms.
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PROTECTIVE ANTIGEN OF HÆMOPHILUS PERTUSSIS

The Lancet, 1954
L, PILLEMER, L, BLUM, I H, LEPOW
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[Protective antigen of influenza virus].

Nihon rinsho. Japanese journal of clinical medicine, 1998
Influenza A virus is unique among human viruses in its capacity to alter the antigenic phenotype with relative ease and evade neutralizing antibodies. This property is ascribed to the accumulation of a series of amino acid changes in the antigenic regions of hemagglutinin (HA) molecule.
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Yersinia pseudotuberculosis protective antigens

Vaccine, 1992
G.Y. Tseneva, V.M. Bondarenko
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Protective antigens in experimental schistosomiasis

Acta tropica. Supplementum, 1987
Capron, A., Pierce, R., Balloul, J.M.
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[Search for protective antigens of hookworms].

Wiadomosci parazytologiczne, 2007
Hookworms are very important blood sucking nematode parasites of humans and domestic animals. The host with a heavy infection can lose almost a cup of blood per day. This may contribute to anemia which is associated with many physical and mental developmental insults.
Marcin, Wiśniewski, Ewa, Długosz, Piotr, Baska, Halina, Wedrychowicz   +3 more
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