Results 101 to 110 of about 2,244,388 (313)

Incidence and determinants of stillbirth among women who gave birth in Jimma University specialized hospital, Ethiopia

open access: yesThe Pan African Medical Journal, 2017
INTRODUCTION: Worldwide approximately 2.7 million are stillborn, more than 98% of these occur in developing countries. To address the problem, incidence and determinants of stillbirth must be understood.
Dejene Tilahun, Tsion Assefa
doaj   +1 more source

Sadder but fitter. The evolutionary function of depressive symptoms following fetal loss [PDF]

open access: yes, 2004
A literature review about an evolutionary model of fetal loss depression is presented. This model conceptualizes depression following miscarriage or stillbirth as an evolutionary protective mechanism to avoid further fetal loss.
Binser, Martin J.   +6 more
core   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

open access: yesFEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga   +3 more
wiley   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

Does Religion/Spirituality Modify the Association of Stressful Life Events and Suicidal Ideation in Australian Men?

open access: yesReligions, 2018
In a large population cohort of Australian men, we previously observed that stressful life events were associated with increased suicidal ideation (SI).
Karolina Krysinska   +3 more
doaj   +1 more source

Developing site-specific guidelines for orchard soils based on bioaccessibility – Can it be done? [PDF]

open access: yes, 2008
Horticultural land within the periurban fringe of NZ towns and cities increasingly is being developed for residential subdivision. Recent surveys have shown that concentrations of As, Cd, Cu, Pb, and ΣDDT (sum of DDT and its degradation products DDE and ...
Gaw, Sally K.   +4 more
core  

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

The Effectiveness of Life Skills Training on Reduction of the Risk and Enhancement of the Protective Factors against Drug Abuse for Delinquency Children in Reformatory Place

open access: yesResearch on Addiction, 2013
Objective: the aim of this study was investigation the effectiveness of life skills training on reducing the risk factor and enhancement of protective factors in city of Hamadan reformatory place for delinquency children.
Mohsen Ahmadi, T. S   +2 more
doaj  

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