Results 101 to 110 of about 1,176,869 (313)
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
An investigation into the risk and protective factors associated with youth offending
, 2010 This thesis examines risk and protective factors associated with youth offending and how these have been applied to legislation, prevention and intervention.
Vien, Anh
core
Molecular Oncology, EarlyView.In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source
Background There are increasing efforts to better understand suicidal behaviour among current and former military personnel in Australia. More research using innovative methodologies is needed to identify risk and protective factors that could be ...
Donaldson, Alex +9 more
core +1 more source
Socio-environmental factors associated with the risk of contracting Buruli ulcer in Tiassalé, South Côte d'Ivoire : a case-control study [PDF]
, 2016 Buruli ulcer (BU) is a cutaneous infectious disease caused by Mycobacterium ulcerans. The exact mode of transmission remains elusive; yet, some studies identified environmental, socio-sanitary, and behavioral risk factors.
Gerd Pluschke +20 more
core +1 more source
Molecular Oncology, EarlyView.Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano +6 more
wiley +1 more source
Risk and Protective Factors in addiction Proneness among High School Adolescents
Salāmat-i ijtimā̒ī, 2018 Background and Objective: Some unfavorable social and family settings increase the person's vulnerability to substance abuse and predispose a person to addiction. This study aims to investigate the risk and protective factors of addiction proneness among
Ali Zeinali, Hassan-Pasha sharifi
doaj
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
Protective Factors Against Breast Cancer Development: A Retrospective Study on Breastfeeding and Fertility [PDF]
Objective: Breast cancer (BC) is the most common type of cancer among women. Various risk and protective factors play a role in its development. This study evaluates the association between parity, breastfeeding, and age at BC diagnosis among women with ...
Rümeysa YEGİN +6 more
core +1 more source