Results 91 to 100 of about 1,176,869 (313)

Phosphoinositides and inositol phosphates as molecular glues

open access: yesFEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry   +9 more
wiley   +1 more source

Risk and protective factors of stranger and acquaintance violence victimisation in England and Wales.

open access: yes, 2016
Violence has been fallen dramatically over the past decades. However, it is still unclear why there is an overall decline in violence in and outside the UK.
Ganpat, Soenita Minakoemarie   +5 more
core  

Protective factors associated with young passenger intervening in risky driving situations

open access: yes, 2012
While the negative influence of passengers on driving is usually studied, young passengers may protect against young drivers’ crash involvement by speaking out and trying to stop unsafe driving behavior.
Foss, Melissa S., Buckley, Lisa
core   +1 more source

PARK(ing) time–How park deficiency affects the biological clock in a Drosophila model of Parkinson's disease

open access: yesFEBS Letters, EarlyView.
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara   +3 more
wiley   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

Does Religion/Spirituality Modify the Association of Stressful Life Events and Suicidal Ideation in Australian Men?

open access: yesReligions, 2018
In a large population cohort of Australian men, we previously observed that stressful life events were associated with increased suicidal ideation (SI).
Karolina Krysinska   +3 more
doaj   +1 more source

Risk and protective factors for self-harm thoughts and behaviours in transgender and gender diverse people: A systematic review

open access: yes
Background: Self-harm (any self-injury or -poisoning regardless of intent) is highly prevalent in transgender and gender diverse (TGD) populations. It is strongly associated with various adverse health and wellbeing outcomes, including suicide.
Townsend, E.   +11 more
core   +1 more source

The need for research on human factors regarding personal protective devices in the cold environment

open access: yes, 1996
The human factors or wearability needs of personal protective devices (ppd) and clothing (ppc) worn in the cold environment become more important as they must compromise with, and be adapted to, the clothing worn for cold protection.
Abeysekera, John D. A.,   +1 more
core   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

The Effectiveness of Life Skills Training on Reduction of the Risk and Enhancement of the Protective Factors against Drug Abuse for Delinquency Children in Reformatory Place

open access: yesResearch on Addiction, 2013
Objective: the aim of this study was investigation the effectiveness of life skills training on reducing the risk factor and enhancement of protective factors in city of Hamadan reformatory place for delinquency children.
Mohsen Ahmadi, T. S   +2 more
doaj  

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