Results 131 to 140 of about 2,244,388 (313)
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Insights into a long life without cancer: The case of the bowhead whale
Molecular Oncology, EarlyView.Long‐lived, large‐bodied organisms have evolved powerful anticancer mechanisms that preserve cellular and tissue integrity across extended lifespans. A recent study by Firsanov et al. shows that greater genome stability is a key factor underlying the remarkable longevity and cancer resistance of one such species, the bowhead whale.
Inés Paniagua, Johanna A. Joyce
wiley +1 more source
MedicinaBackground and Objectives: In the context of disease prevention, interaction on an additive scale is commonly assessed to determine synergistic effects between exposures.
Andrea Nova +2 more
doaj +1 more source
Silent voices : supporting children and young people affected by parental alcohol misuse [PDF]
, 2012 Main table of contents: • Summary of Key Messages and Recommendations • Section One: Background • Section Two: Methodology • Section Three: Consultation with children and young people • Section Four: Review Findings • Research ...
Adamson, Jon, Templeton, Lorna
core
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Gout Knowledge: A Survey of Australian Outpatients with Gout
Open Access Rheumatology: Research and ReviewsAthena Chin,1 Robert J Adams,2 Tiffany K Gill,3 Catherine L Hill1,4 1Rheumatology Unit, The Queen Elizabeth Hospital, Woodville South, South Australia, Australia; 2Flinders Health and Medical Research Institute – Sleep Health, Flinders University ...
Chin A, Adams RJ, Gill TK, Hill CL
doaj
Goals and Plans in Protective Decision Making [PDF]
Protective decisions are often puzzling. Among other anomalies, people insure against non-catastrophic events, underinsure against catastrophic risks, and allow extraneous factors to influence insurance purchases and other protective decisions.
David H. Krantz, Howard Kunreuther
core
Molecular Oncology, EarlyView.A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel +12 more
wiley +1 more source
Risk and protective factors for bullying [PDF]
, 2012 U posljednjih 10-ak godina istraživanja međuvršnjačkog nasilja usmjerila su se na brojne rizične i zaštitne faktore. U ovom radu pobliže ćemo prikazati te faktore koristeći 4 razine ekološkog modela: individualna, obiteljske i druge bliske veze, škola i ...
Velki, Tena
core +2 more sources
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source