Results 151 to 160 of about 1,147,833 (267)

Threonine 348 regulates the subcellular localization of PTEN

FEBS Open Bio, EarlyView.
Thr348 in the C2 domain is a key contributor to PTEN subcellular localization. The PTEN350 fragment and PTENA4 accumulated in the nucleus, whereas PTENK13R,A4 predominantly localized to the plasma membrane. In contrast, substitution of Thr348 with Asp (T348D) disrupted these characteristic localization patterns, resulting in predominant cytoplasmic ...
Takashi Kato, Suzu Tanaka, Miyu Ohashi
wiley   +1 more source

Correction to: Siblings in families of children with chronic disorders: a model of risk and protective factors. [PDF]

J Pediatr Psychol
europepmc   +1 more source

Present or absent: risks and protective factors of sudden infant death syndrome (SIDS) in the Zambian context. [PDF]

J Glob Health
Zulu E, Mwananyanda L, Pieciak R, Forman L, Shah J, Gill CJ, Chilengi R, Payne-Lohman B, Duffy C, Osei-Poku G, Thea D, Somwe SW, Herlihy JM.   +12 more
europepmc   +1 more source

BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells

FEBS Open Bio, EarlyView.
BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley   +1 more source

Risk and Protective Factors for Suicide Mortality in Youths: A Systematic Review and Meta-Analysis.

JAMA Netw Open
Geoffroy MC, Baker-Sullivan E, Nitu NJ, Civita A, Boruff J, Sinyor M, Robinson J, MacDonald K, Anzarouth L, Chartrand E, Iyer SN, Langevin R, Pirkis J, Thombs B.   +13 more
europepmc   +1 more source

Protocol for a systematic literature review on risk and protective factors for non-suicidal self-injurious behavior among adolescents in Iran. [PDF]

PLoS One
Erfanifar B, Modders M, Massar K.
europepmc   +1 more source

Protective Factors in Midlife

The detection of psychological variables with a positive impact on health during middle age is of great interest. The data of 393 middle-aged participants (aged 35–45 at T1 and 45–55 at T2) of the National Survey of Midlife Development in the United States (MIDUS) were analyzed to investigate the associations between health, optimism, positive affect,
Dainese, Sara M., Allemand, Mathias, Ribeiro, Nadja, Bayram, Sanem, Martin, Mike, Ehlert, Ulrike   +5 more
openaire   +1 more source

MARK4 enhances stress granule formation under oxidative stress and increases tau accumulation

FEBS Open Bio, EarlyView.
MARK4 (red dots) localizes to stress granules (orange dots) and promotes their formation under oxidative stress by modulating TIA1 (blue dots). MARK4 and TIA1 synergistically increase tau (purple) accumulation, and the reduction of the TIA1 ortholog suppresses neurodegeneration in a fly model.
Sho Nakajima, Kotone Watanabe, Grigorii Sultanakhmetov, Aoi Fukuchi, Keiya Ito, Sawako Shimizu, Taro Saito, Akiko Asada, Kanae Ando   +8 more
wiley   +1 more source

Preventing the Cycle of Violence: Protective Factors Among Ugandan Male Youth With Histories of Childhood Violence. [PDF]

J Interpers Violence
Chiang LF, Picchetti V, Howard A, Apondi R, Wasula L, Cheptoris J, Aluzimbi G, Hegle J, Stamatakis C, Logan JE, Massetti GM.   +10 more
europepmc   +1 more source

Recent insights into the molecular mechanism of ubiquinol oxidation by cytochrome bc1

FEBS Open Bio, EarlyView.
The review reflects on the mechanism of the catalytic reaction in cytochrome bc1: the electron bifurcation that involves the separation of two electrons derived from the quinol oxidation to opposite sides of the enzyme across the membrane. This review summarizes the long‐standing effort to understand the mechanism of quinol oxidation catalyzed by ...
Anna Wójcik‐Augustyn, Artur Osyczka, Marcin Sarewicz   +2 more
wiley   +1 more source