Results 61 to 70 of about 1,176,869 (313)
Protective factors contributing to wellbeing among refugee youth in Australia
, 2018 The present study examined protective factors associated with the wellbeing of 93 youth from a refugee background resettled in Brisbane, Australia. Wellbeing was defined as an absence of psychological distress and the presence of subjective wellbeing ...
Khawaja, Nigar G. +2 more
core +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Journal of Nursing PracticeBackground: Developing resilience among family caregivers of schizophrenia patients is challenging. Families must be able to identify risk factors and manage them to achieve a dynamic family situation and have the ability to survive while caring for ...
Faizatur Rohmi +2 more
doaj +1 more source
Multi-Level Protective Factors of Adolescent Smoking and Drinking
European Journal of Investigation in Health, Psychology and Education, 2023 Adolescence is the most critical life stage for experimentation with substance use; however, this is also the most suitable period for strengthening protective factors and thus promoting adult physical and mental health.
Réka Dudok, Bettina F. Piko
doaj +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Is rumination a risk and a protective factor?
Europe’s Journal of Psychology, 2017 High trait positive affect (PA) protects against depressive symptoms through cognitive responses such as rumination. However, how rumination in response to positive emotions (positive rumination) protects against depressive symptoms while rumination in response to negative emotions (brooding) predicts depressive symptoms is poorly understood.
Kaitlin A. Harding, Amy Mezulis
openaire +3 more sources
Exploring expert insights on early years risk and protective factors for long-term marital sustainability [PDF]
The first five years of marriage are a crucial period for sustaining relationships, especially in Malaysia, where a growing number of marriages end in divorce, with financial stress being a primary cause.
Zafri, Aisya Vania +4 more
core +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source