Results 101 to 110 of about 9,382,737 (353)

Antibodies to the N-terminal block 2 of Plasmodium falciparum merozoite surface protein 1 are associated with protection against clinical malaria.

, 2004
This longitudinal prospective study shows that antibodies to the N-terminal block 2 region of the Plasmodium falciparum merozoite surface protein 1 (MSP-1) are associated with protection against clinical malaria in an area of stable but seasonal malaria ...
Conway, David J, David R. Cavanagh, Cavanagh, D R, Jana S. McBride, McBride, Jana S, Jørgen A. L. Kurtzhals, Akanmori, B D, Kurtzhals, Jørgen, Dodoo, Daniel, Hviid, L, Kurtzhals, J A L, Polley, S, Spencer Polley, Cavanagh, David R, Polley, Spencer, Thor G. Theander, Cavanagh, David, Dodoo, D, Koram, K, Hviid, Lars, Daniel Dodoo, Akanmori, Bartholomew D, Theander, Thor G, McBride, J S, Koram, Kojo, Kurtzhals, Jørgen AL, Kojo Koram, Conway, D J, Theander, T G, Lars Hviid, Bartholomew D. Akanmori, David J. Conway   +31 more
core   +1 more source

Surface stability test plan for protective barriers [PDF]

, 1989
Natural-material protective barriers for long-term isolation of buried waste have been identified as integral components of a plan to isolate a number of Hanford defense waste sites.
Ligotke, M. W.
core   +1 more source

Optimization design of stress relief coalbed methane surface well in a high-gas mine

Frontiers in Earth Science
Coalbed methane drainage through surface wells has become increasingly important in high-gas mines. Surface wells are prone to different types of deformations and failures owing to mining-induced effects.
Junhui Fu, Guangcai Wen, Bichuan Zhang, Haitao Sun, Rifu Li, Jiaqi Liu   +5 more
doaj   +1 more source

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

Molecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder, Klaas de Lint, Hồ Mỹ Phúc Võ, Mariana M. Góis, Rosalie A. Kampen, Marta San Martin Alonso, Ilse Nootenboom, Veronica Garzero, Tiemen J. Wendel, Rob M. F. Wolthuis, Sylvie M. Noordermeer   +10 more
wiley   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Friction parameter surface treated concrete with a remedy against dryness [PDF]

Строительство уникальных зданий и сооружений, 2014
The article devoted to developing techniques for measuring the parameters of road friction and airfield pavements in order to study the influence of external factors on the slip resistance of concrete surfaces treated with care products ...
Yuri Germanovich Barabanshchicov, Vitalij Anatolievich Gatiullin, Muhanna Ala   +2 more
doaj  

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Calculation of the hydraulic characteristics of the protective coating used in trenchless technologies for the construction and renovation of pipelines to extend their service life

MATEC Web of Conferences, 2017
The lifetime of the pipeline, which undergoes trenchless repair by pulling and then fixing various types of internal protective coatings inside, is determined by the strength characteristics of the two-layer structure “old pipeline + internal protective ...
Orlov Vladimir, Zotkin Sergey, Dezhina Irina, Zotkina Irina   +3 more
doaj   +1 more source

Effectiveness of Protective Action of Coatings from Moisture Sorption into Surface Layer of Sand Moulds

Archives of Metallurgy and Materials, 2016
The results of investigations of the sorption process of surface layers of sand moulds covered by zirconium and zirconium - graphite alcohol coatings are presented in the paper. Investigations comprised two kinds of sand grains (silica sand and reclaimed
Kaźnica N., Zych J.
doaj   +1 more source

Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

Molecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski, Liudmyla Dolinchuk, Michał Jerzak, Albert Gandurski, Tomasz Grochowski, Weronika Wojtyś, Maciej Zadrożny, Wojciech Kaźmierczak, Małgorzata Lenarcik, Marta Matejak‐Górska, Radosław Samsel, Tomasz Olesiński, Dawid Walerych   +12 more
wiley   +1 more source