Results 81 to 90 of about 9,382,737 (353)

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Control of Magnesium Alloy Corrosion through the Use of Engineered Intermetallics [PDF]

open access: yes, 2014
The low density and high relative strength of Mg alloys means they can offer engineering benefits over steels or Al alloys. However, the susceptibility of Mg alloys to corrosion has limited their exploitation and restricted their use to more benign ...
Pidcock, Andrew
core  

Influence of laser surface texturing on surface microstructure and mechanical properties of adhesive joined steel sheets

open access: yes, 2009
This work discusses the resultant microstructure of laser surface treated galvanised steel and the mechanical properties of adhesively bonded surfaces therein. The surface microstructure obtained at laser intensities between 170 and 1700 MW cm 22 exhibit
SAKATA, F. Y.   +4 more
core   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

CORROSION BEHAVIOUR OF THE AZ31 MAGNESIUM ALLOY AND SURFACE TREATMENTS FOR ITS CORROSION PROTECTION

open access: yes, 2009
Nowadays environmental conservation forces the transportation industry to manufacture lighter and low emissions transport vehicles. In this contest, magnesium alloys have found increasing attention by the automotive industry because of their low density ...
Zanotto, Federica
core  

Lake-Sunapee-Protective-Association/LMP: LSPA LMP database 1986-2023

open access: yes
<p><em>Code and Data Description:</em></p> <p>The code contained in this release documents the quality control measures that have been made to collate the data from the Lake Sunapee Protective Association’s (LSPA) Long-
Weathers, Kathleen   +2 more
core   +1 more source

2015 International Conference on Textile Science and Engineering (CTSE 2015) [PDF]

open access: yes, 2015
Sunlight is a known skin carcinogen. Skin cancer is the most common form of cancer in humans, and typically affects sun-exposed parts of the body. Clothing provides a protective barrier that reduces the amount of ultraviolet radiation (UVR) reaching the ...
Harrison, Simone, Downs, Nathan
core  

An investigation of naphthalenediimides as central building blocks in model compounds for scanning tunneling microscope induced light emission experiments and förster resonance energy transfer studies [PDF]

open access: yes, 2010
Scanning tunnelling microscopy (STM) is a powerful technique to observe surfaces at the atomic level. The resolution of this STM technique is good enough to study the electronic properties of single molecules adsorbed onto metallic substrates.
Gabutti, Sandro
core   +1 more source

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

open access: yesMolecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute   +4 more
wiley   +1 more source

Altered patterns of gene expression underlying the enhanced immunogenicity of radiation-attenuated schistosomes [PDF]

open access: yes, 2008
Schistosome cercariae only elicit high levels of protective immunity against a challenge infection if they are optimally attenuated by exposure to ionising radiation that truncates their migration in the lungs.
Jason Skelton   +21 more
core   +1 more source

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