Results 171 to 180 of about 944,964 (246)

Cytoskeleton–Membrane Uncoupling in Duchenne Muscular Dystrophy: Implications for Newborn Screening and Early Protection

Cytoskeleton, EarlyView.
ABSTRACT The cytoskeleton of striated muscle integrates force transmission, mechanotransduction, and sarcolemmal stability through coordinated networks of sarcomeres, costameres, and intermediate filaments. Together, these systems establish mechanical continuity between the contractile apparatus, the sarcolemma, and the extracellular matrix.
Houda Cohen, Nora Hosny, Brian R. Thompson, Joseph M. Metzger   +3 more
wiley   +1 more source

The PROtective VEntilation (PROVE) Network - advancing research and collaboration in mechanical ventilation. [PDF]

Crit Care Sci
Schultz MJ, Ball L, Bernardi M, Battaglini D, Buiteman LA, Ferreira JC, Abreu MG, Rosa S, Hemmes SN, Huhle R, Mazzinari G, Meenen DMPV, Nasa P, Serpa Neto A, Pelosi P, Paulus F, Robba C, Rocco PRM, Scharffenberg M, Tschernko E, Wittenstein J.   +20 more
europepmc   +1 more source

Experimental study on burning rate and flame geometry in construction tunnel fires under high geothermal conditions

Deep Underground Science and Engineering, EarlyView.
Abstract As tunnel construction advances in lengths and depths, the construction of tunnels in high geothermal environments has become increasingly common, raising significant fire risks. In this study, a 1:20 scale model tunnel test platform was constructed to investigate the effects of a high geothermal environment on fire behavior in tunnels during ...
Xiaoxian Fei, Maozhen Liu, Jiayi Ha, Linbo Du, Zhi Li, Yuhao Li, Chuangang Fan   +6 more
wiley   +1 more source

A prospective clinical evaluation of new ECCO2R technology in mild to moderate ARDS patients: assessing ultra-lung-protective ventilation with PRISMALUNG. [PDF]

Crit Care
Combes A, Levy B, Tapponnier R, Capellier G, Mekontso Dessap A, Duburcq T, Castelain V, Forel JM, Uhel F, Mayaux J, Goldstein J, Kurz J, Harenski K, Montgomery W, Parreno R, Jaber S.   +15 more
europepmc   +1 more source

Multiple injection techniques to stimulate complex fracture networks in coal reservoirs: A case study on gas disaster reduction of subsurface coal mine in southwest China

Deep Underground Science and Engineering, EarlyView.
An experimental device for physical simulation of hydraulic fracturing, comprising: a load‐bearing mechanism with multiple interconnected plates that collectively form an sample chamber; a load‐generating mechanisms, with multiple load‐generating mechanisms arranged within the experimental chamber.
Delei Shang, Farui Shi, Jun Lu, Minghui Li, Cunbao Li, Heping Xie   +5 more
wiley   +1 more source

Lung-protective ventilation strategy in acute respiratory distress syndrome: a critical reappraisal of current practice. [PDF]

Crit Care
Park KJ.
europepmc   +1 more source

Strengthening urban resilience in China through underground infrastructures management: Addressing global climate challenges with technological solutions

Deep Underground Science and Engineering, EarlyView.
This paper explores how climate‐resilient technologies, such as smart grids, digital twins, and self‐healing materials, can enhance urban resilience. It highlights the urgent need for proactive planning, public‐private collaboration, and data‐driven innovation to future‐proof underground infrastructure amid accelerating climate and urban pressures ...
Kai Chen Goh, Tonni Agustiono Kurniawan, Christia Meidiana, Abdelkader Anouzla, Faissal Aziz, Imran Ali, Joan Cecilia C. Casila, M. Imran Khan, Dongdong Zhang, Meihui Jiang, Mohd Hafiz Dzarfan Othman, Md Munir Hayet Khan, Kasun Kumara Dissanayake   +12 more
wiley   +1 more source

Mechanical Protective Ventilation: New Paradigms in Thoracic Surgery. [PDF]

J Clin Med
Canbaz M, Şentürk E, Şentürk M.
europepmc   +1 more source

Fracture evolution of a thick soft protection layer and the water inrush mechanism in overburden under longwall mining

Deep Underground Science and Engineering, EarlyView.
Through shear–tensile creep tests and viscoelastic modeling, the fracture evolution of thick soft protective layers is clarified. Results show thickness‐dependent rheological failure modes that govern four types of roof water inrush, providing a mechanism‐based framework for hazard prediction and control. Abstract In the Jurassic coal‐bearing strata of
Mengnan Liu, Wei Qiao, Xianggang Cheng, Xiangsheng Meng, Peichao Feng   +4 more
wiley   +1 more source

EIT-guided individualized PEEP titration versus conventional lung-protective ventilation to prevent pulmonary complications in laparoscopic bariatric surgery: a study protocol for a randomized controlled trial. [PDF]

BMC Anesthesiol
Guo N, Ren Y, Liu M, Chen L, Wang X, Wu G, Li X, Feng Y, Li M, Wei C, Sun Y, Wu J.   +11 more
europepmc   +1 more source