Results 101 to 110 of about 128,382 (221)

Changes in urine dipstick proteinuria and risk of dialysis-requiring acute kidney injury and subsequent ESRD

open access: yesScientific Reports
Acute kidney injury (AKI) is associated with poor prognosis. Dialysis-requiring AKI and end-stage renal disease (ESRD) represents the severe form of AKI. Proteinuria is a reliable prognostic factor for kidney diseases.
Sung Keun Park   +9 more
doaj   +1 more source

Research Progress of Berberine in Kidney Disease: Targeting Mitochondria and Ferroptosis

open access: yesiNew Medicine, EarlyView.
This figure illustrates the model‐specific renoprotective mechanisms of berberine (BBR) across three major kidney diseases. From left to right, the diagram shows that BBR targets distinct core pathways depending on the pathological context: in diabetic nephropathy (DN), BBR activates AMPK to improve mitochondrial energy metabolism; in acute kidney ...
Liuqing Wang   +3 more
wiley   +1 more source

Análise dos resultados maternos e perinatais de 244 casos de hipertensão arterial na gravidez - Maternidade Carmela Dutra no período de fevereiro de 1991 à abril de 1998. [PDF]

open access: yes, 1999
Trabalho de Conclusão de Curso - Universidade Federal de Santa Catarina, Centro de Ciências da Saúde, Departamento de Tocoginecologia, Curso de Medicina, Florianópolis ...
Oliveira, Ygor Vieira de
core  

GSK3β drives early diabetic tubulopathy via TFEB‐mediated mitochondrial dysfunction

open access: yesInterdisciplinary Medicine, EarlyView.
Mitochondrial dysfunction, including mitochondrial biogenesis, mitophagy, dynamics and oxidative stress, occurs in the early stages of diabetic tubulopathy, which precede proteinuria and renal histological changes. GSK3β is a potential novel biomarker for the prediction of diabetic tubulopathy.
Lan Yao   +10 more
wiley   +1 more source

Proteinúria e ácido úrico sérico maternos em pacientes com síndrome de HELLP [PDF]

open access: yes, 2012
Objective: To evaluate the association of maternal serum uric acid (UA) and proteinuria with clinical and demographic data of pregnant women with preeclampsia syndrome (PES) complicated by HELLP syndrome. Methods: One hundred and nine pregnant women were
Cunha, Hilda Helena Souza
core   +1 more source

Exploring the Chemical Complexity and Toxicological Behaviour of Semi‐permanent Make‐Up Pigments: A Systematic Review

open access: yesJournal of Applied Toxicology, EarlyView.
ABSTRACT Semi‐permanent make‐up (SPMU), or micropigmentation, involves implanting pigments into the dermal layer of the skin for cosmetic enhancement. Unlike topical cosmetics, which are rapidly cleared from the body, SPMU pigments persist in living tissues, raising unique toxicological considerations.
T. A. N. Kaye   +3 more
wiley   +1 more source

Epigenetically Regulated NOX4/NRF2 Axis Mediates PM2.5‐Induced Ferroptosis and Inflammatory Response in Membranous Nephropathy

open access: yesJournal of Applied Toxicology, EarlyView.
ABSTRACT This study aims to explore the involvement and mechanism of ferroptosis in particulate matter 2.5 (PM2.5)–induced membranous nephropathy (MN) progression. A cationic bovine serum albumin (cBSA)–induced mouse model of MN was established, followed by PM2.5 exposure.
Yanhong Gao   +8 more
wiley   +1 more source

Deep Learning‐Assisted Classification of Urinary Red Blood Cell Morphology for Glomerular Hematuria Screening: A Pilot Study

open access: yesJournal of Clinical Laboratory Analysis, EarlyView.
This retrospective pilot study developed a YOLOv5l‐based deep learning system to detect and classify urinary red blood cells as isomorphic, dysmorphic, or unknown in urine sediment images. The model achieved a precision of 0.84, recall of 0.69, and F1‐score of 0.76 for dysmorphic RBCs, while sample‐level morphology scoring showed preliminary ...
Yih‐Lon Lin   +4 more
wiley   +1 more source

Old disease, new twist

open access: yesJournal of Hospital Medicine, EarlyView.
Abstract An 81‐year‐old man with a history of high‐grade urothelial carcinoma of the bladder and ureter on treatment with atezolizumab and tiragolumab presented to the emergency department with 5 months of malaise, generalized weakness, and fatigue and 2 weeks of subjective fevers. One month prior to presentation, he received an empiric 9‐day course of
Hadi Roudsari   +4 more
wiley   +1 more source

Long‐term clinical trajectory of microvillus inclusion disease associated with STXBP2‐related familial hemophagocytic lymphohistiocytosis type 5: A case report

open access: yesJournal of Parenteral and Enteral Nutrition, EarlyView.
Abstract Familial hemophagocytic lymphohistiocytosis type 5 is caused by biallelic pathogenic variants in STXBP2, which encodes syntaxin‐binding protein, a key regulator of vesicle trafficking. In addition to immune dysregulation, patients with familial hemophagocytic lymphohistiocytosis type 5 may present with severe, persistent diarrhea associated ...
Hiroyuki Tanaka   +5 more
wiley   +1 more source

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