Results 151 to 160 of about 14,861 (235)

Forsythiaside A Alleviates Kidney Injury and Intestinal Epithelium Dysfunction in IgA Nephropathy by Inhibiting TLR4/NF‐κB Signaling

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT IgA nephropathy (IgAN), the most common form of glomerulonephritis, is a major and growing public health issue. It results from intestinal barrier dysfunction that leads to mesangial deposition of pathogenic galactose‐deficient IgA1 (Gd‐IgA1) and renal inflammation.
Meng‐Si Li, Kai Liu
wiley   +1 more source

ASSOCIAÇÃO DA EXCREÇÃO URINÁRIA DE SÓDIO DE 24 HORAS COM A PROTEINÚRIA NO DECLÍNIO DA FUNÇÃO RENAL

open access: gold
Elisângela Milhomem Dos Santos   +5 more
openalex   +2 more sources

Correlation Between Bladder Debris and Abnormal Urinalysis: Health Warnings and Research Prospects in Elderly Patients

open access: yesMedicine Bulletin, EarlyView.
ABSTRACT Background Ultrasound‐detected bladder debris is hypothesized to reflect urinary tract inflammation or infection, yet its clinical significance in older adults, a population with high asymptomatic urinary tract infections (UTI) rates and diagnostic challenges, remains poorly characterized.
Qian Lin   +5 more
wiley   +1 more source

Association of proteinuria with various clinical findings and morphologic variables of oxford classification in immunoglobulin a nephropathy patients

open access: yesInternational Journal of Preventive Medicine, 2013
Background: Immunoglobulin A nephropathy (IgAN) with nephrotic syndrome is an uncommon form of IgAN. Clinical and morphological characteristics of proteinuria in IgAN, especially when is in nephrotic range have not yet been fully examined. This study was
Hamid Nasri   +6 more
doaj  

The Evolving Landscape of Immunotoxicity: Charting Mechanisms and Future Strategies for Immune Checkpoint Inhibitor Adverse Events

open access: yesMed Research, EarlyView.
ABSTRACT The use of immune checkpoint inhibitors (ICIs) has significantly improved the efficacy of cancer therapy, but their associated immune‐related adverse events (irAEs) can severely compromise treatment safety. This review systematically summarizes the core mechanisms underlying irAEs, which include multi‐organ damage resulting from T‐cell ...
Anqi Lin   +8 more
wiley   +1 more source

Association between serum bicarbonate and low mid‐upper arm circumference in patients with non‐dialysis‐dependent chronic kidney disease: A cross‐sectional study

open access: yesNutrition in Clinical Practice, EarlyView.
Abstract Background Although previous experimental studies showed that metabolic acidosis promoted muscle catabolism and impaired protein synthesis, few epidemiological studies reported an independent association between serum bicarbonate levels and muscle atrophy in patients with chronic kidney disease (CKD).
Nobuhisa Morimoto   +13 more
wiley   +1 more source

Fibroblast‐specific palladin drives kidney fibrosis via MRTF–SRF signaling

open access: yesThe Journal of Pathology, EarlyView.
Abstract Fibrosis is a common end‐stage pathway of progressive chronic kidney diseases. Previously we demonstrated that myocardin‐related transcription factor (MRTF)–serum response factor (SRF) signaling drives the expression of fibrosis‐related molecules through actin cytoskeleton dynamics in renal fibroblasts.
Naoki Yamamoto   +27 more
wiley   +1 more source

SÍNDROME NUTCRACKER E PROTEINÚRIA

open access: gold
Maria Antônia Vianna Santos¹   +5 more
openalex   +2 more sources

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